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首页> 外文期刊>Research Journal of Medical Sciences >Homocysteine Levels in Early Spontaneous Abortus
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Homocysteine Levels in Early Spontaneous Abortus

机译：早期自然流产的同型半胱氨酸水平

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The discovery that hyperhomocysteinemia may be responsible for several pregnacy complications has only recently been made. With this study, it is aimed to determine levels of homocysteine in pregnant women encountered with abortus imminens, abortus incompletus and abortus. In the study in 35 abortus imminens, 36 abortus incompletus, 30 abortus missed and 33 healthy pregnant women, homocysteine levels are specified by making use of competitive immunoassay technique. Homocysteine levels were determined in the abortus imminens group as 8.78±5.29 μmol L-1 in the abortus incompletus group as 10.55±4.49 μmol L-1, in abortus missed group as 9.03±4.29 μmol L-1 and as 4.87±1.27 μmol L-1 in the control group. Homocysteine levels were found to be excessively high with all abortus groups when compared to the control group (p<0.0001). The homocysteine levels of pregnant individuals using folic acid (7.354±3.78 μmol L-1) in comparison to those not using (9.58±5.27 μmol L-1) was determined as significantly low (p<0.01). As a result of this study, it cannot be explained that all abortus develop in parallel with hyperhomocysteinemia. However, hyperhomocysteinemia is together with an increased risk of abortus and such a risk might possibly be reduced with use of folic acid, it should definitely be recommended to use folic acid.
机译：高同型半胱氨酸血症可能与几种妊娠并发症有关的发现是最近才发现的。通过这项研究，其目的是确定遇到流产即将发作，流产不全和流产的孕妇体内的同型半胱氨酸水平。在这项研究中，对35例流产即将发生，36例流产不全，30例流产遗漏和33例健康孕妇，通过竞争性免疫测定技术确定了同型半胱氨酸水平。流产次要组中同型半胱氨酸水平确定为8.78±5.29μmolL-1，流产不全组中确定为10.55±4.49μmolL-1，流产遗漏组中确定为9.03±4.29μmolL-1和4.87±1.27μmolL.对照组为-1。与对照组相比，所有流产组的同型半胱氨酸水平都过高（p <0.0001）。与未使用叶酸（9.58±5.27μmolL-1）的孕妇相比，使用叶酸（7.354±3.78μmolL-1）的孕妇的同型半胱氨酸水平显着降低（p <0.01）。这项研究的结果不能解释所有流产与高同型半胱氨酸血症同时发生。但是，高同型半胱氨酸血症会增加流产的风险，使用叶酸可能会降低这种风险，因此绝对建议使用叶酸。

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