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The Effects of Medication on Activity and Rehabilitation of Older People – Opportunities and Risks

机译：药物对老年人活动和康复的影响-机会和风险

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Multiple medication use, or polypharmacy, is common in people undergoing rehabilitation. Polypharmacy is also common in older people, where it has the potential to impact on habitual physical activity. Despite this, the interactions between medication, disease, activity, and rehabilitation outcomes are insufficiently researched. In this review, we consider common classes of medications that can affect physical activity levels and outcomes of rehabilitation. We consider medications that improve disease processes and improve limiting symptoms (eg, breathlessness in heart failure and lung disease, pain in arthritis), unwanted side effects of medications (eg, central slowing caused by opioids and hypnotics), and also medication classes that might have the ability to improve activity and rehabilitation outcomes via beneficial effects on neuromuscular function (eg, angiotensin-converting enzyme inhibitors). We conclude by giving practical advice on how to review and optimise medication use to support habitual physical activity and ensure the best results from rehabilitation.
机译：在接受康复治疗的人中，经常使用多种药物或多药治疗。多元药房在老年人中也很常见，它可能会影响习惯的体育锻炼。尽管如此，药物，疾病，活动和康复结果之间的相互作用还没有得到足够的研究。在这篇综述中，我们考虑了会影响身体活动水平和康复结果的常见药物类别。我们考虑的药物可以改善疾病进程并改善限制性症状（例如，心衰和肺病的呼吸困难，关节炎的疼痛），药物的不良副作用（例如，由阿片类药物和催眠药引起的中枢性减慢），以及可能有能力通过对神经肌肉功能的有益作用（例如，血管紧张素转换酶抑制剂）改善活动和康复结果。最后，我们提供有关如何审查和优化药物使用以支持习惯性体育锻炼并确保康复的最佳结果的实用建议。

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