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首页> 外文期刊>Rehabilitation Process and Outcome >Bleeding Events in Thrombocytopenic Patients With Cancer Undergoing Acute Rehabilitation:
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Bleeding Events in Thrombocytopenic Patients With Cancer Undergoing Acute Rehabilitation:

机译:接受急性康复治疗的血小板减少症患者的出血事件:

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Objectives:To determine incidence of bleeding in thrombocytopenic patients with cancer undergoing acute inpatient rehabilitation.Design:This is an observational cross-sectional retrospective study.Setting:Acute inpatient academic rehabilitation facility.Participants:Adult patients admitted to acute inpatient rehabilitation with functional impairments secondary to cancer.Methods:Electronic records were reviewed for thrombocytopenic patients with cancer to determine platelet counts, bleeding events during rehabilitation, and anticoagulant medications prescribed.Main outcomes measurements:Type and number of bleeding events, severity of bleeding by World Health Organization criteria.Results:Of the 278 patients with cancer admitted to acute rehabilitation over a 27-month time frame, 119 had at least one platelet count <150?000/μL. In all, 37 (31.1%) had a history of a bleeding event prior to the rehabilitation admission and 34 (28.6%) had at least one bleeding complication during their stay. Most events (87.5%) were of low grade (Grade 1 and 2 World Health Organization criteria). There was no association between platelet counts <11?000 or counts 11?000 to 20?000/μL and the occurrence of bleeding (P ?=?.106 and P ?=?.319, respectively). Although anticoagulants were common, there was no association found with a bleeding event and either anticoagulation status (receiving or not on such agents), specific anticoagulant or antiplatelet agents, or a combination.Conclusions:Bleeding events in patients with cancer with thrombocytopenia during acute rehabilitation stay are not uncommon but are typically mild in severity and not associated with the degree of thrombocytopenia. Patients taking anticoagulants when platelet levels rose did experience bleeding events, but not at a statistically greater rate than those not taking such medications.
机译:目的:确定接受急性住院康复治疗的血小板减少性癌症患者的出血发生率设计:这是一项横断面观察性回顾性研究背景:急性住院学术康复设施参与者:成年患者因功能障碍继而接受急性住院康复方法:审查电子记录的血小板减少症癌症患者,以确定血小板计数,康复期间的出血事件和处方的抗凝药物主要结果测量:出血事件的类型和数量,出血严重程度(根据世界卫生组织的标准)。 :在27个月的时间里接受急性康复治疗的278名癌症患者中,有119名至少有一个血小板计数<150?000 /μL。总共37例(31.1%)有康复入院前的出血事件史,34例(28.6%)在其住院期间至少有一次出血并发症。大多数事件(87.5%)属于低等级(世界卫生组织1级和2级标准)。血小板计数<11?000或计数11?000至20?000 /μL与出血的发生之间没有关联(分别为 P?= ?. 106和 P?= ?. 319) 。尽管抗凝剂很常见,但未发现与出血事件和抗凝状态(接受或未接受抗凝剂),特定抗凝剂或抗血小板药或其组合相关。结论:急性康复期间患有血小板减少症的患者的出血事件停留并不少见,但严重程度通常较轻,与血小板减少程度无关。当血小板水平升高时服用抗凝剂的患者确实发生了出血事件,但在统计学上没有比不服用此类药物的患者高。

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