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首页> 外文期刊>Research Journal of Medical Sciences >Acceleration of Wound Healing Potential by Lantana camara Leaf Extract in Experimental Rats
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Acceleration of Wound Healing Potential by Lantana camara Leaf Extract in Experimental Rats

机译：马Lan丹提取物对实验大鼠的伤口愈合潜能的促进作用

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The ethanolic extract of Lantana camara leaf was evaluated for their wound healing potential in rats. Four groups of adult male Wistar albino rats were experimentally wound in the posterior neck area. A thin layer of blank placebo was applied topically to wounds of Group 1. Wound of Group 2 and 3 animals were dressed with a thin layer of placebo containing 5 and 10% L. camara extract, respectively. A thin layer of intrasite gel was applied topically to wounds of Group 4 animals as reference. The effects of these topical applicants on the rate of wound healing and histology were assessed. Wound dressed with placebo containing plant extracts significantly healed earlier than those treated with blank placebo. Wounds dressed with placebo containing 10% extract significantly accelerate wound healing activity compared to wounds dressed with placebo containing 5% extract. Histological analyses of healed wounds confirmed the results. Wounds dressed with placebo containing extracts showed markedly less scar width at the wound enclosure and wounds contained large amounts of fibroblast proliferation and more mature and densely packed collagen with accompanying angiogenesis compared to wounds dressed only with blank placebo. We conclude that L. camara extract significantly enhanced the acceleration rate of wound enclosure in rats.
机译：评价马Lan丹（Latana camara）叶的乙醇提取物在大鼠中的伤口愈合潜力。实验性地将四组成年雄性Wistar白化病大鼠在后颈区伤口。将薄薄的空白安慰剂局部施用于组1的伤口。将第2组和第3组动物的伤口用分别包含5％和10％的Camara提取物的安慰剂薄层包扎。将薄层的部位内凝胶局部施用于第4组动物的伤口作为参照。评估了这些外用申请人对伤口愈合速度和组织学的影响。用含植物提取物的安慰剂包扎的伤口比用空白安慰剂治疗的伤口早愈合。与用含5％提取物的安慰剂包扎的伤口相比，用含10％提取物的安慰剂包扎的伤口可显着加速伤口愈合活性。伤口愈合的组织学分析证实了结果。与仅用空白安慰剂处理的伤口相比，用含安慰剂的提取物处理的伤口在伤口处的疤痕宽度显着减小，并且伤口含有大量成纤维细胞增殖，并且胶原蛋白更加成熟和密集，并伴有血管生成。我们得出的结论是，Camara L. camara提取物显着提高了大鼠伤口包裹的加速速率。

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