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首页> 外文期刊>Revista colombiana de obstetricia y ginecologie >Comparación entre el clivaje temprano y el estadio pronuclear como parámetros de referencia para inducir el embarazo en pacientes ovoreceptoras en Cali (Colombia)
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Comparación entre el clivaje temprano y el estadio pronuclear como parámetros de referencia para inducir el embarazo en pacientes ovoreceptoras en Cali (Colombia)

机译：在卡利（哥伦比亚），卵裂早期和早期分裂作为诱导卵母细胞受体妊娠的参考参数的比较

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Introduction: some authors have proposed that non-invasive embryo implantation methods (based on early cleavage or pronuclear stage for two cells 25 and 27 hours post-insemination) are applicable to in vitro fertilisation programmes, thereby increasing the probability of implantation and pregnancy. Objective: comparing pregnancy rates in patients implanted with embryos originating from early cleavage to those from the pronuclear stage. Methodology: a retrospective cohort study was carried out. Embryo implantation patients were included who had been attending the FECUNDAR -Biomedicine Centre in Cali, Colombia, from April 2004 to December 2007 who presented a poor responsetothecontrolledovarianstimulationcycle, age factor and/or ovarian failure and pregnancy substitute patients. The sample consisted of 45 patients; 36 patients (79%) were expected to become pregnant in the early-syngamy and cleavage group (group 1) and 9 patients (21%) in the pronuclear group (group 2). Implantation and pregnancy rates were determined and the Chi-square (X2) test was used for comparing both groups. Results: 183 of the 289 zygotes complied with the proposed parameters (i.e. embryos from early cleavage, syngamy and pronuclear stage 25 and 27 hours post-insemination); 79% of these 183 came from the early cleavage and syngamy stage and 21% from the pronuclear stage. Three embryos on average were transferred to embryo implantation patient; average age was 38, the pregnancy rate obtained when transferring early cleavage embryos was 44% compared to 41% for non-cleaved embryo transfer 25 hours post-insemination. No statistically significant differences were found regarding how pregnancy was induced. Conclusion: equal success rates were obtained for both procedures in the given study conditions.
机译：简介：一些作者提出非侵入性胚胎植入方法（基于授精后25和27小时的两个细胞的早期分裂或前核阶段）适用于体外受精程序，从而增加了植入和怀孕的可能性。目的：比较植入早期分裂胚胎与原核阶段胚胎的妊娠率。方法：进行回顾性队列研究。包括从2004年4月至2007年12月在哥伦比亚卡利的FECUNDAR-生物医学中心就诊的胚胎植入患者，他们对受控制的卵巢刺激周期，年龄因素和/或卵巢衰竭以及妊娠替代患者的反应较差。样本包括45例患者。早期的同卵裂和解理组（组1）预期有36例（79％）怀孕，而原核组（组2）则有9例（21％）怀孕。确定植入率和妊娠率，并使用卡方（X2）检验比较两组。结果：289个受精卵中的183个符合建议的参数（即，在授精后25和27小时的早期卵裂，合子和前核阶段的胚胎）;在这183个中，有79％来自卵裂和合子的早期阶段，而有21％来自前核阶段。平均将三个胚胎转移到胚胎植入患者中。平均年龄为38岁，在转移早期卵裂胚胎后获得的妊娠率为44％，而在授精后25小时进行非卵裂胚胎移植时为41％。关于如何诱发妊娠，没有发现统计学上的显着差异。结论：在给定的研究条件下，两种手术的成功率均相等。

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