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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Oral leukoplasia in a pediatric patient with primary deficiency of T lymphocytes
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Oral leukoplasia in a pediatric patient with primary deficiency of T lymphocytes

机译：小儿原发性T淋巴细胞缺乏症的小儿口腔白斑增生

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Presence off recurrent infections caused by uncommon germs related to appearance of frequent complications and associated with allergic and autoimmune and/or tumor manifestations, are characteristic of primary immunodeficiencies. Authors present the case of a white male child aged 12, with backgrounds of viral, bacterial and parasitic, recurrent and severe infections, from the first months of life, with a diagnosis of non-homogenous oral leukoplasia of tongue, supported by histopathology. Viral study showed the presence of antibodies specific to viral capsid and of nuclear antigen of Epstein-Barr virus. Immunologic studies showed the presence of a primary immunodeficiency of T lymphocytes. There were not alterations in serum concentrations of immunoglobulins, the complement and the phagocytic function. Surgical removal of lesion and the use of immunomodulation contributed to a favorable course of patient.
机译：原发性免疫缺陷的特征是由与常见并发症的出现相关的罕见细菌引起的复发性感染，以及与变态反应和自身免疫和/或肿瘤表现有关。作者介绍了一个12岁的白人男孩的病例，该病例从出生的头几个月起就具有病毒，细菌和寄生虫，反复发作和严重感染的背景，并被组织病理学诊断为舌头非均质性口腔白斑。病毒研究表明存在针对病毒衣壳的特异性抗体和爱泼斯坦-巴尔病毒的核抗原。免疫学研究表明存在T淋巴细胞原发性免疫缺陷。血清免疫球蛋白，补体和吞噬功能没有改变。手术切除病灶和使用免疫调节有助于改善患者病程。

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