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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Updating in transplant of hematopoietic progenitor cells in pediatric patients during the past 15 years
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Updating in transplant of hematopoietic progenitor cells in pediatric patients during the past 15 years

机译：过去15年间小儿患者造血祖细胞移植的更新

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In the past year 2010, it was commemorate the 25 Anniversary of introduction in Cuba of the bone marrow transplantation and its development has followed the sequence of the universal history of the hematopoietic transplantation. In present paper authors made reference to more important achievements over the past 15 years including the introduction of the transplantation with mobilized cell to peripheral blood. Partial results of a comparative study of 2 groups of pediatric patients are showed; one received hematopoietic progenitor cells obtained from the bone marrow and other with cells mobilized to the peripheral blood by means of hematopoietic growth factors. Other advances include: the introduction of non-myeloablation transplantation in 2002, the application of recombinant factors produced in Cuba in the management of transplanted patients and the introduction of chimerism. Different features related to histocompatibility are analyzed as well as the requirements to improve the transplantation results. It is indicated the contribution of the experience obtained with this procedure for the development of the regenerative medicine.
机译：在过去的一年中，它是为纪念在古巴引进骨髓移植25周年，其发展遵循了造血移植的普遍历史。本文作者参考了过去15年中更重要的成就，包括将动员细胞移植到外周血中。显示了对两组儿科患者进行比较研究的部分结果。一个接受了从骨髓获得的造血祖细胞，另一个接受了通过造血生长因子动员到外周血的细胞。其他进展包括：2002年引入非清髓性移植，古巴生产的重组因子在移植患者管理中的应用以及嵌合体的引入。分析了与组织相容性有关的不同特征，以及对改善移植结果的要求。表明了通过该程序获得的经验对再生医学的发展的贡献。

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