The current concepts of the importance of the adhesion molecules in the physiopathology of drepanocytic anemia are presented. The permanent subclinic inflammatory process of'/> Importance of the adhesion molecules in the physiopathology of drepanocytic anemia
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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Importance of the adhesion molecules in the physiopathology of drepanocytic anemia
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Importance of the adhesion molecules in the physiopathology of drepanocytic anemia

机译：粘附分子在腹膜红细胞性贫血的生理病理学中的重要性

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> face="Verdana" size="2">The current concepts of the importance of the adhesion molecules in the physiopathology of drepanocytic anemia are presented. The permanent subclinic inflammatory process of the disease in its basal condition, as well as the different alterations in the expression of these molecules during the episodes of vasoocclusive crisis, are described. The most significant aspects on the present therapy are reviewed and a future integrated polytherapy is suggested. The importance of the drepanocyte/vascular endothelium interaction in the onset of the inflammatory response is discussed as a physiopathological basis of the disease in the abscence of inflammatory processes.
机译：> face =“ Verdana” size =“ 2”>介绍了粘连分子在七细胞性贫血的生理病理学中的重要性的当前概念。描述了该疾病在其基础状态下的永久性亚临床炎症过程，以及在血管闭塞性危象发作期间这些分子表达的不同变化。本文对目前治疗方法中最重要的方面进行了综述，并提出了未来的综合治疗方案。讨论了在炎症反应缺乏时，脾脏细胞与血管内皮细胞相互作用的重要性，作为该疾病的生理病理基础。

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