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首页> 外文期刊>Revista Cubana de Ortopedia y Traumatología >Autologous bone marrow stem cells transplant to intervertebral disc
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Autologous bone marrow stem cells transplant to intervertebral disc

机译：自体骨髓干细胞移植到椎间盘

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Introduction: stem cell transplant was performed in seven patients diagnosed with degenerative one intervertebral disc. Objective: evaluate the safety and tolerance of the procedure to transplanted cells. Methods: cells were extracted from the patient's own bone marrow. They were isolated by the Ficoll-Hypaque method and they were implemented in discs selected as grades II and III according to Pfirrmann classification resonance imaging. Graft outcomes were evaluated one year later. Results: no significant adverse events were recorded from the procedure or graft cells. By using the Oswestry index, clinical outcomes were evaluated as beneficial, as well as the possible improvement in images from magnetic resonance imaging before and a year later. Conclusion: these results show that stem cells derived from the patient's own bone marrow can be safely transplanted with excellent tolerance and no complications using the method described.
机译：简介：干细胞移植在7例被诊断为变性椎间盘的患者中进行。目的：评估该方法对移植细胞的安全性和耐受性。方法：从患者自身的骨髓中提取细胞。通过Ficoll-Hypaque方法将其分离，并根据Pfirrmann分类共振成像将其实施为II级和III级光盘。一年后评估移植结果。结果：手术或移植细胞未见明显不良反应。通过使用Oswestry指数，临床结果被评估为有益，以及一年前和一年后来自磁共振成像的图像可能得到改善。结论：这些结果表明，使用所述方法可以安全地移植源自患者自身骨髓的干细胞，且耐受性极佳，且无并发症。

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