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首页> 外文期刊>Revista Paulista de Pediatria >Prevalence and clinical characteristics of wheezing in children in the first year of life, living in Cuiabá, Mato Grosso, Brazil
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Prevalence and clinical characteristics of wheezing in children in the first year of life, living in Cuiabá, Mato Grosso, Brazil

机译：居住在巴西马托格罗索州Cuiabá的第一年儿童喘息的患病率和临床特征

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OBJECTIVE: To evaluate the prevalence and the clinical characteristics of wheezing in infants aged 12 to 15 months in the city of Cuiabá, Mato Grosso State, Midwest Brazil.METHODS: Parents and/or guardians of infants were interviewed and completed a written standardized questionnaire of the Estudio Internacional de Sibilancia en Lactantes (EISL) - phase 3 at primary healthcare clinics at the same day of children vaccination or at home, from August of 2009 to November of 2010.RESULTS: 1,060 parents and/or guardians completed the questionnaire, and 514 (48.5%) infants were male. Among the studied infants, 294 (27.7%) had at least one episode of wheezing during the first year of life, beggining at 5.8±3.0 months of age, with a predominance of male patients. The prevalence of occasional wheezing (3 episodes of wheezing) was 15.0% and recurrent wheezing (≥3 episodes) was 12.7%. Among the infants with recurrent wheezing, the use of inhaled β2-agonist, oral corticosteroid, leukotriene receptor antagonist, as well as night symptoms, respiratory distress, and hospitalization due to severe episodes were significantly more frequent. Physician-diagnosed asthma was observed in 28 (9.5%) of the wheezing infants. Among the wheezing infants, 80 (27.7%) were diagnosed with pneumonia, of whom 33 (11.2%) required hospitalization; neverthless, no differences between occasional and recurrent wheezing infants were found.CONCLUSIONS: The prevalence of recurrent wheezing and physician-diagnosed asthma in infants were lower compared with those observed in other Brazilian studies. Recurrent wheezing had early onset and high morbity.
机译：目的：评估巴西中西部马托格罗索州Cuiabá市12至15个月大的婴儿喘息的患病率和临床特征。方法：采访了婴儿的父母和/或监护人，并填写了一份书面的标准化问卷从2009年8月至2010年11月，在儿童接种疫苗当天或在家中，初级卫生保健诊所的Estudio Internacional de Sibilancia en Lactantes（EISL）第3阶段。结果：1,060名父母和/或监护人填写了问卷，并且514名（48.5％）婴儿为男性。在接受研究的婴儿中，有294（27.7％）岁以下的婴儿在出生后的第一年内至少有一次喘鸣发作，在5.8±3.0个月大时开始乞wh，其中以男性患者居多。偶发性喘息（<3次喘息）的患病率为15.0％，复发性喘息（≥3次发作）为12.7％。在反复喘息的婴儿中，吸入β2-激动剂，口服皮质类固醇，白三烯受体拮抗剂以及严重症状引起的夜间症状，呼吸窘迫和住院的发生率明显增加。在28名（9.5％）的喘息婴儿中观察到了医生诊断的哮喘。在喘息婴儿中，有80名（27.7％）被诊断出患有肺炎，其中33名（11.2％）需要住院治疗;结论：与其他巴西研究相比，婴儿反复发作气喘和经医生诊断的哮喘患病率较低。反复喘息发作较早，发病率较高。

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