首页> 外文期刊>Romanian Journal of Biophysics >MODULATION BY QUERCETIN OF THE EFFECT OF CERTAIN HOFMEISTER ANIONS ON ARTIFICIAL LIPID BILAYERS
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MODULATION BY QUERCETIN OF THE EFFECT OF CERTAIN HOFMEISTER ANIONS ON ARTIFICIAL LIPID BILAYERS

机译:槲皮素对某些HOFMEISTER阴离子对人工脂类涂层的影响的调制

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Our paper investigates, by means of the black lipid membranes (BLM) technique, the effect of the natural flavonoid quercetin (QCT) on the electrical parameters of artificial phospholipidic membranes subjected to the action of Hofmeister anions (chloride, nitrate, acetate) in different concentrations. Quercetin shows a modulator effect on the anion-induced electrical parameters changes of lipid bilayers. As suggested by our results, quercetin acts by insertion in the artificial membrane, as well as by influencing the anion-lipid interactions. Our results indicate that the effects of quercetin and Hofmeister anions are not summative, which points out complex interactions in the membrane-anions-quercetin system.
机译:我们通过黑脂膜(BLM)技术研究了天然黄酮类槲皮素(QCT)在不同的Hofmeister阴离子(氯离子,硝酸根,乙酸根)作用下对人工磷脂膜电参数的影响浓度。槲皮素对脂质双层的阴离子诱导的电参数变化具有调节作用。正如我们的结果所暗示的那样,槲皮素通过插入人造膜中以及影响阴离子-脂质相互作用来发挥作用。我们的结果表明,槲皮素和霍夫迈斯特阴离子的作用不是累加的,这表明膜-阴离子-槲皮素系统中存在复杂的相互作用。

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