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首页> 外文期刊>Romanian Journal of Biophysics >RHEOLOGICAL AND ELECTRICAL BEHAVIOR OF ERYTHROCYTES IN PATIENTS WITH DIABETES MELLITUS
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RHEOLOGICAL AND ELECTRICAL BEHAVIOR OF ERYTHROCYTES IN PATIENTS WITH DIABETES MELLITUS

机译：糖尿病患者红细胞的流变和电学行为

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摘要

Diabetes mellitus is a disease in which the body does not produce enough, or properly respond to, insulin, a hormone produced in the pancreas. The rheological and electrical properties of red blood cells in the patients with diabetes have been studied in order to assess the complications of the disease. There was an increase in the viscosity and the yield stress of diabetic erythrocyte comparing to the normal. These may lead to the increase in the aggregation and decreased in deformability of red blood cells due to reducing the negative surface electric charge. The rheological disorders could lead to microcirculation problems. On the other hand, the relative permittivity, dielectric loss, and AC conductivity of diabetic erythrocyte increased significantly compared to the control. This is due to the toxic effects of glucose on erythrocytes which lead to restructuring of erythrocytes membranes. The high glucose value lead to imbalance of electrolyte in red blood cell membrane and the dielectric spectroscopy (DS) is very sensitive to such slight changes.
机译：糖尿病是一种机体，无法产生足够的胰岛素，也不会对胰脏中产生的激素胰岛素作出适当的反应。为了评估疾病的并发症，已经研究了糖尿病患者中红细胞的流变学和电学性质。与正常人相比，糖尿病红细胞的粘度和屈服应力有所增加。这些可能由于减少的负表面电荷而导致聚集的增加和红细胞的可变形性的降低。流变性可能导致微循环问题。另一方面，与对照组相比，糖尿病红细胞的相对介电常数，介电损耗和交流电导率显着增加。这是由于葡萄糖对红细胞的毒性作用导致了红细胞膜的重组。高葡萄糖值导致红细胞膜中电解质的不平衡，介电谱（DS）对这种微小变化非常敏感。

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