...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Kurume Medical Journal >THE MODIFYING EFFECTS OF BACTERIAL SUBSTANCES IN THE COURSE OF INFECTION WITH NEUROTROPIC VIRUSIII. REPORT. THE MODE OF THE INHIBITORY EFFECT OF BACTERIAL SUBSTANCES RELATED E. COLI ON THE NEUROTROPIC VIRUS INFECTION STUDIED IN THE SUSPENDED TISSUE CULTURE
【24h】

THE MODIFYING EFFECTS OF BACTERIAL SUBSTANCES IN THE COURSE OF INFECTION WITH NEUROTROPIC VIRUSIII. REPORT. THE MODE OF THE INHIBITORY EFFECT OF BACTERIAL SUBSTANCES RELATED E. COLI ON THE NEUROTROPIC VIRUS INFECTION STUDIED IN THE SUSPENDED TISSUE CULTURE

机译：神经营养病毒感染过程中细菌物质的修饰作用。报告。大肠杆菌相关细菌物质对悬浮组织培养中神经营养病毒感染的抑制作用模式

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The E. coli was selected among the bacteria having inhibitory effect described in the previous reports (1) (2), and the experiments concerning the inhibitory effect of E. coli on the GDVII strain of mouse encephalomyelitis virus (GDVII virus) were investigated in detail (3) (4). The results obtained were the following data: the administration with E. coli before virus inoculation was effective on the inhibition of the infection with the GDVII virus, but when the E. coli was given to the mice follo wing the virus infection the effect of the bacteria was not evident; it was most significant in the case of the same route of administration with the bacteria and the virus; the bacteria itself had not direct virucidal activity; the effect of the bacteria was not related with the antibody against this bacteria; and no evidence of inapparent infection in the survival mice was presented. Therefore it would be assumed that the inhibitory effect of E. coli on the virus infection might prevent the invasion or penetration of the virus into the susceptible cells.The purpose of this paper is to report a part of the kinetics of the inhibitory effect of E. coli on the virus infection by using the suspended tissue culture method which is available to clarification of the mechanism of the effects. It is favorable for an introduction of the tissue culture into series experiments that the effect of E. coli exsisted in the bacterial cells and was thermostabile.
机译：从先前报道（1）（2）中所述的具有抑制作用的细菌中选择大肠杆菌，并于2006年对涉及大肠杆菌对GDVII鼠脑脊髓炎病毒（GDVII病毒）抑制作用的实验进行了研究。细节（3）（4）。获得的结果是以下数据：在病毒接种之前给予大肠杆菌可有效抑制GDVII病毒的感染，但是当在感染病毒后给小鼠以大肠杆菌时，大肠杆菌的作用细菌不明显;对于细菌和病毒的相同给药途径，这是最重要的;细菌本身没有直接的杀病毒活性;细菌的作用与针对该细菌的抗体无关。并没有在存活小鼠中出现隐性感染的证据。因此，可以认为大肠杆菌对病毒感染的抑制作用可能阻止了病毒向易感细胞的入侵或渗透。本文的目的是报告大肠杆菌抑制作用的动力学的一部分。大肠杆菌通过使用悬浮组织培养法对病毒感染的作用，可用于阐明其作用机理。对于将组织培养物引入系列实验是有利的，大肠杆菌的作用存在于细菌细胞中并且是热稳定的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号