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Cutaneous Myoepithelioma: A Case Report of an Unusual and Recently Recognized Entity

机译:皮肤肌上皮瘤:一个不寻常且最近被认可的实体的病例报告

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Myoepitheliomas and mixed tumors were only recently recognized to occur primarily in soft tissue, and only small case numbers have been described. The present case is a 25?year?old male who had solitary, painless mass over the right middle finger, measuring 3 cm in greatest dimensions, and light microscopy revealed a tumor composed of a mixed population of the spindle, epithelioid, and plasmacytoid cells arranged around a central chondromyxoid stroma. No definite diagnosis could be reached on this morphology, and initial diagnosis of benign mixed stromal tumor was considered. Immunohistochemistry was performed and the tumor showed strong positivity for calponin and smooth muscle actin, Ki?index showed low index, weak, and focal positivity for S?100 and negative for pan?cytokeratin. The final diagnosis of benign myoepithelioma was entertained.
机译:肌上皮瘤和混合肿瘤直到最近才被发现主要发生在软组织中,仅描述了少量病例。本例为一名25岁男性,右中指单处无痛,最大尺寸为3厘米,光学显微镜检查发现肿瘤由纺锤体,上皮样细胞和浆细胞样细胞混合组成排列在中央软骨粘膜基质周围。此形态尚无明确诊断,因此考虑初步诊断为良性混合间质瘤。进行了免疫组织化学分析,肿瘤显示出对钙蛋白和平滑肌肌动蛋白的强阳性,Ki?指数显示出对S?100的低指数,弱和局部阳性,而泛细胞角蛋白则呈阴性。最终诊断为良性肌上皮瘤。

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