Rare Incidental Occurrence of Mantle Cell Lymphoma with Alcoholic Liver Disease and Pancreatitis

Rateesh Sareen; Menka Kapil; G N Gupta; Dinesh Agrawal

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Rare Incidental Occurrence of Mantle Cell Lymphoma with Alcoholic Liver Disease and Pancreatitis

机译：很少发生酒精性肝病和胰腺炎的套细胞淋巴瘤

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We present an extremely rare case of Mantle cell Lymphoma with concomitant alcoholic liver disease and pancreatitis in a 48 year old male patient. There was absence of abdominal lymphadenopathy. The complete blood count showed absolute lymphocytosis which on subsequent peripheral blood examination showed small to medium sized atypical cells raising suspicion of prolymphocytic leukemia. The flow cytometry and Immunohistochemistry examination confirmed Mantle cell lymphoma. The morphology of cells in mantle cell lymphoma are known to mimic prolymphocytes on peripheral blood. However, the rare concomitant occurrence of both diseases makes the case an interesting one for readers and emphasizes on the usefulness of peripheral blood examination although not completely diagnostic but raising an alarm for the diagnosis of this rare lymphoma.

机译：我们介绍了一名48岁男性患者中极少见的伴有酒精性肝病和胰腺炎的Mantle细胞淋巴瘤病例。没有腹部淋巴结肿大。全血细胞计数显示绝对淋巴细胞增多，其在随后的外周血检查中显示出小到中等大小的非典型细胞，增加了对前淋巴细胞白血病的怀疑。流式细胞仪和免疫组织化学检查证实了套细胞淋巴瘤。已知套细胞淋巴瘤中的细胞形态模仿外周血中的淋巴细胞。然而，两种疾病的罕见同时发生使该病例成为读者的有趣话题，并强调了外周血检查的有用性，尽管这种诊断并非完全可诊断，但对这种罕见淋巴瘤的诊断提出了警告。

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《Oncology, Gastroenterology and Hepatology Reports》 |2018年第1期|共4页
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Rateesh Sareen; Menka Kapil; G N Gupta; Dinesh Agrawal;
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1. Diabetes Mellitus Predicts Occurrence of Cirrhosis and Hepatocellular Cancer in Alcoholic Liver and Non-alcoholic Fatty Liver Diseases [J] . Evan J.Raff, Donny Kakati, Joseph R.Bloomer, 临床与转化肝病杂志（英文版） . 2015,第001期

机译：糖尿病可预测酒精性肝和非酒精性脂肪肝疾病的肝硬化和肝细胞癌的发生
2. Diabetes Mellitus Predicts Occurrence of Cirrhosis and Hepatocellular Cancer in Alcoholic Liver and Non-alcoholic Fatty Liver Diseases [J] . Evan J.Raff, Donny Kakati, Joseph R.Bloomer, 临床与转化肝病杂志（英文版） . 2015,第001期

机译：糖尿病预测酒精性肝脏和非酒精脂肪肝疾病中肝硬化和肝细胞癌的发生
3. Mantle cell lymphoma and chronic lymphocytic leukemia: report of a rare disease association and review of the literature [J] . Joana Perdigão, Helena Alaiz, Paulo Lúcio, Journal of Hematopathology . 2010,第2a3期

机译：套细胞淋巴瘤和慢性淋巴细胞性白血病：罕见疾病协会的报告和文献复习
4. Liver mitochondrial DNA4977 deletion in alcoholic fatty liver disease and relation to ultrasound [C] . Zhuang Liwei, Liang Tao, Fu Yili 2011 IEEE/ICME International Conference on Complex Medical Engineering . 2011

机译：酒精性脂肪肝患者肝线粒体DNA 4977 的缺失及其与超声的关系
5. Studies of the adduction of hepatocellular proteins by 4-HNE in animal models of alcoholic liver disease: Systematic analysis of hepatocellular Erk 1/2 modulation and dysregulation of the Erk-Elk-AP1 signal transduction pathway. [D] . Sampey, Brante P. 2005

机译：酒精性肝病动物模型中4-HNE加合肝细胞蛋白的研究：肝细胞Erk 1/2调节和Erk-Elk-AP1信号转导通路失调的系统分析。
6. Diabetes Mellitus Predicts Occurrence of Cirrhosis and Hepatocellular Cancer in Alcoholic Liver and Non-alcoholic Fatty Liver Diseases [O] . Evan J. Raff, Donny Kakati, Joseph R. Bloomer, 2015

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Rare Incidental Occurrence of Mantle Cell Lymphoma with Alcoholic Liver Disease and Pancreatitis

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