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Interstitial Lung Diseases Associated with Connective Tissue Pathologies: Radiologic Features

机译:间质性肺疾病与结缔组织病理学相关:放射学特征

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Introduction : The high resolution computed tomography (HRCT) is an important part in the diagnostic approach of interstitial lung disease (ILD) associated with connective tissue diseases (CTD) by providing detailed information on the elementary lesion and the radiological pattern of ILD. Aim : to point out the role of HRCT in the diagnosis of ILD associated with CTD (ILD-CTD). Methods : A Retrospective descriptive study was conducted between 2008 and 2017. Data of 24 patients presenting ILD-CTD were collected. A review of HRCT was performed by a radiologist without knowledge of the CTD. Results: Predominant elementary lesion of ILD associated with dermatomyositis (9 cases) was ground glass opacity (n = 9) followed by consolidation (n = 6). Non Specific Interstitial Pneumonia (NSIP) was the most reported pattern (5 cases). Ground glass opacity was also the predominant elementary lesion for the 2 cases of scleroderma and in Sj &#246 gren’s syndrome (4 cases/5). NSIP was the predominant radiological presentation in these two CTD. Lymphoid interstitial pneumonia revealed Sj &#246 gren’s syndrome in one case. In rheumatoid arthritis (6 cases), the elementary HRCT lesions were irregular interlobular septal thickening (n = 4) and honeycombing (n = 4) consistent with Usual Interstitial Pneumonia (UIP) in 2 cases. Similarly UIP has been described for the 2 patients with lupus and mixed connective tissue disease. Conclusion: HRCT plays an important role in the management of ILD-CTD. Description of the HRCT elementary lesions and the radiological pattern of ILD can be helpful for CTD’s diagnosis.
机译:简介:高分辨率计算机断层扫描(HRCT)通过提供有关基本病变和ILD放射学模式的详细信息,是间质性肺病(ILD)与结缔组织疾病(CTD)相关的诊断方法的重要组成部分。目的:指出HRCT在诊断CTD相关的ILD(ILD-CTD)中的作用。方法:回顾性描述性研究在2008年至2017年进行。收集了24例表现为ILD-CTD的患者的数据。放射科医师对HRCT进行了回顾,但并不了解CTD。结果:与皮肌炎相关的ILD的主要原发灶(9例)为磨玻璃片混浊(n = 9),随后是实变(n = 6)。非特异性间质性肺炎(NSIP)是报告最多的模式(5例)。磨玻璃样混浊也是2例硬皮病和Sj&#246 gren's综合征(4例/ 5)的主要基本病变。 NSIP是这两个CTD的主要放射学表现。淋巴样间质性肺炎1例显示Sj&#246 gren综合征。在类风湿性关节炎(6例)中,基本HRCT病变为不规则小叶间间隔增厚​​(n = 4)和蜂窝状(n = 4),与通常的间质性肺炎(UIP)一致2例。类似地,已针对2名狼疮和混合性结缔组织病患者描述了UIP。结论:HRCT在ILD-CTD的管理中起着重要作用。 HRCT基本病变的描述和ILD的放射学特征可有助于CTD的诊断。

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