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首页> 外文期刊>Open Journal of Pathology >Proliferative Brenner Tumor with Borderline Mucinous Cystadenocarcinoma of the Ovary in a 75-Year-Old Woman
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Proliferative Brenner Tumor with Borderline Mucinous Cystadenocarcinoma of the Ovary in a 75-Year-Old Woman

机译：75岁妇女卵巢增生性Brenner肿瘤伴交界性粘液性膀胱腺样腺癌

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摘要

We report here an extremely rare case of proliferative Brenner tumor with borderline mucinous cystadenocarcinoma of the ovary, metastasizing to the pleura in a 75-year-old woman. Massive pleural effusion were present due to metastasis and pseudo-Meigs’ syndrome. The cytological findings from pleural effusion, ascites and tumor imprint were similar, suggesting mucus-producing malignant tumors. After receiving a thoracic drainage for pleural effusion, the patient underwent an exploratory laparotomy to remove the left-ovarian tumor. Histopathological examination revealed proliferative Brenner ovarian tumor with borderline mucinous cystadenocarcinoma, and immunohistochemical examinations for the tumors, even mucus-rich tumor cells were positive for CK 7 and negative for CK 20, suggesting the tumor arising from transitional cells, not from mucus-producing ovarian surface epithelial tumor cells. She underwent four courses of chemotherapy with paclitaxel and carboplatin. The patient showed no signs of recurrence 16 months after the surgery.
机译：我们在这里报告了一个极罕见的增生性Brenner肿瘤病例，其卵巢交界性粘液性囊腺癌，转移至一名75岁女性的胸膜。由于转移和假性Meigs综合征而出现大量胸腔积液。胸腔积液，腹水和肿瘤印记的细胞学发现相似，提示产生粘液的恶性肿瘤。接受胸腔积液胸腔引流后，患者进行了探查性剖腹术以切除左卵巢肿瘤。组织病理学检查显示增生性Brenner卵巢肿瘤伴黏液性囊腺癌，并对该肿瘤进行免疫组织化学检查，即使是富含粘液的肿瘤细胞对CK 7阳性也对CK 20阴性，这表明该肿瘤是由移行细胞而非产生粘液的卵巢引起的表面上皮肿瘤细胞。她接受了紫杉醇和卡铂化疗的四个疗程。术后16个月，患者未见复发迹象。

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