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首页> 外文期刊>International journal of gynecological pathology: Official journal of the International Society of Gynecological Pathologists >Mucinous tumor of low malignant potential ('borderline' or 'atypical proliferative' tumor) of the ovary: a study of 171 cases with the assessment of intraepithelial carcinoma and microinvasion.
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Mucinous tumor of low malignant potential ('borderline' or 'atypical proliferative' tumor) of the ovary: a study of 171 cases with the assessment of intraepithelial carcinoma and microinvasion.

机译：卵巢低恶性黏液性肿瘤（“边界”或“非典型增生性”肿瘤）：对171例上皮内癌和微浸润情况进行评估的研究。

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Mucinous tumors of the ovary are a continuing source of controversy in the field of gynecologic pathology. We examined a series of 171 intestinal-type mucinous tumors of low malignant potential ("borderline" or "atypical proliferative" tumors) to clarify the clinical significance of intraepithelial carcinoma (IECA) and microinvasion (area /=IC (P=0.002), microinvasion (P=0.013), age less than 45 years (P=0.032), and IECA (P=0.042). The amount of IECA >/=10% was also associated with the risk of recurrence (P=0.007). Among tumors with microinvasion, there was no significant association between the clinicopathologic variables and recurrence. When considering tumors with stage >/=IC, tumor recurrence was significantly associated with IECA >/=10% (P=0.031) and age less than 45 years (P=0.047). It is important that mucinous tumors of low malignant potential should be staged and be optimally sampled for pathologic examination to document the status of the external surface or peritoneal involvement and to identify the worst degree of epithelial proliferation. Tumor stage >/=IC, IECA >/=10%, microinvasion, and age less than 45 years were the features that were associated with tumor recurrence. The study results also support the use of nuclear grade 3 as the sole criterion of IECA.
机译：卵巢粘液性肿瘤在妇科病理学领域一直是争议之源。我们检查了171例恶性程度低的肠型粘液性肿瘤（“边界线”或“非典型增生性”肿瘤），以阐明上皮内癌（IECA）和微浸润（面积≤10mm）的临床意义。 IECA的诊断是基于明显的核非典型性（3级）。基质间微浸润分为低级和高级（核级为3级）。 171例病例中有67例发生了IECA（39.2％）。微侵袭被确定为31（18.1％），低等级为22（12.9％），高等级为9（5.3％）。已知144例患者的随访状态，其中6例（4.2％）观察到肿瘤复发。复发的危险因素包括国际妇产科联合会> / = IC分期（P = 0.002），微创（P = 0.013），年龄小于45岁（P = 0.032）和IECA（P = 0.042）。 IECA> / = 10％的量也与复发风险相关（P = 0.007）。在微浸润的肿瘤中，临床病理变量与复发之间无显着关联。当考虑阶段> / = IC的肿瘤时，肿瘤复发与IECA> / = 10％（P = 0.031）和年龄小于45岁（P = 0.047）显着相关。重要的是，应分期进行恶性程度低的粘液性肿瘤，并对其进行最佳取样以进行病理检查，以记录外表面或腹膜受累的状况，并确定最坏的上皮增殖程度。肿瘤分期> / = IC，IECA> / = 10％，微浸润和年龄小于45岁是与肿瘤复发相关的特征。研究结果还支持使用3级核作为IECA的唯一标准。

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