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首页> 外文期刊>Online journal of biological sciences >Kidney Function Indices in Mice after Long Intake of Agaricus brasiliensis Mycelia (=Agaricus blazei, Agaricus subrufescens) Produced by Solid State Cultivation | Science Publications
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Kidney Function Indices in Mice after Long Intake of Agaricus brasiliensis Mycelia (=Agaricus blazei, Agaricus subrufescens) Produced by Solid State Cultivation | Science Publications

机译：固态培养产生的巴西姬松茸菌丝体（=姬松茸，姬松茸）的长期摄入对小鼠肾脏功能的影响科学出版物

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> >Problem statement: Agaricus brasiliensis (=Agaricus blazei, Agaricus subrufescens) or Sun mushroom has widespread use for potential health benefits such anti-tumor and immunomodulatory effects. Studies detected that others edible mushrooms affected renal metabolism and despite the widespread use of A. brasiliensis there are no studies that address biological effects on the renal function indices after their oral administration. Therefore, this study had as objective to verify the effects on kidney function indices after long intake of A. brasiliensis mycelium. >Approach: Wheat grains was cultured during 18 days with Agaricus brasiliensis mycelium by solid state culture and used for chown formulation. Groups of female Swiss mice (20 per group) were fed during 14 weeks with 100 and 50% of the formulated feed denominated A100 and A50, respectively. Control group received formulated chown with wheat grains without mycelium. The water intake and excreted urine volume; the physic chemistry analysis of the urine and the serum levels of glucose, proteins, urea, creatinin and uric acid was determined (Meditron Junior-Boehringer, reagent strips Combur 10; microscopy and ADVIA 1650 Bayer). >Results: A100 and A50 groups ingested 19.1 and 15.8% more water compared to C group, respectively. The urine and serum analysis showed that the verified parameters remained invariables for all groups, including glucose levels, which resulted in a 10% reduction of A100 group, without statistical difference (p0.05 Vs C). >Conclusion/Recommendations: The prolonged intake of supplemented feed with A. brasiliensis mycelium didn
机译： > >问题陈述：巴西姬松茸（= Agaricus blazei，姬松茸）或太阳菇已广泛用于潜在的健康益处，例如抗肿瘤和免疫调节作用。研究发现，其他食用菌也会影响肾脏的代谢，尽管巴西曲霉广泛使用，但尚无研究解决口服后对肾功能指数的生物学影响。因此，本研究的目的是验证长期摄入巴西曲霉菌丝体后对肾功能指标的影响。 >方法：将小麦籽粒与巴西姬松茸菌丝体进行固态培养，培养18天，并用于调理配方。每组雌性瑞士小鼠（每组20只）在14周内分别喂食100％和50％的A100和A50配方饲料。对照组接受不含小麦菌丝的小麦籽粒制成的配方猪。进水量和排尿量;测定尿液的物理化学分析以及血清葡萄糖，蛋白质，尿素，肌酐和尿酸的水平（Meditron Junior-Boehringer，试剂条Combur 10;显微镜和ADVIA 1650 Bayer）。 >结果：与C组相比，A100和A50组的摄水量分别增加了19.1和15.8％。尿液和血清分析表明，所有组（包括葡萄糖水平）的已验证参数均保持不变，这导致A100组降低10％，无统计学差异（p> 0.05 Vs C）。 >结论/建议：延长摄入巴西巴西曲霉菌丝体的补料并没有

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