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首页> 外文期刊>Open Journal of Urology >The Serum 25(OH)D Level in Patients with Atypical Femoral Fracture
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The Serum 25(OH)D Level in Patients with Atypical Femoral Fracture

机译：非典型股骨骨折患者的血清25（OH）D水平

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Objective: Excessive curvature of the femur has been considered to be one of the factors associated with atypical femoral fracture (AFF). Although we clarified that femoral curvature was markedly influenced by a low vitamin D level, very few studies have been conducted on the direct relationship between AFF and a serum low level of vitamin D. Therefore, we compared the serum vitamin D level between AFF and osteoporosis patients. Methods: A total of 48 consecutive AFFs in 36 Japanese patients were retrospectively reviewed using the medical records, and 12 consecutive AFFs in 9 patients (AFF group) whose 25-hydroxyvitamin D (25(OH)D) levels were examined were included in this study. As a non-AFF control group, 45 consecutive age-matched female patients with osteoporosis (Osteoporosis group) were enrolled. We compared some laboratory examination items, the bone mineral density, and curvature of the femur. Results: When univariate logistic regression analysis was performed to compare the 2 groups, Ca levels and lateral and anterior curvatures in the AFF group were significantly greater than in the Osteoporosis group (P < 0.05, P < 0.01, and P < 0.01, respectively), and the 25(OH)D level in the AFF group was significantly lower than in the Osteoporosis group (P < 0.01). We used discriminant analysis of these extracted items to exclude the mutual influence of factors and identify factors closely associated with AFF, and 25(OH)D, Ca and anterior curvature were identified as significant items to differentiate these diseases (P < 0.05, P < 0.01, and P < 0.01, respectively). Conclusion: AFF patients showed low vitamin D levels and marked femoral curvatures.
机译：目的：股骨过度弯曲被认为是与非典型股骨骨折（AFF）相关的因素之一。尽管我们澄清了维生素D水平过低会明显影响股骨弯曲，但很少进行关于AFF与血清维生素D含量低之间直接关系的研究。因此，我们比较了AFF与骨质疏松症之间的血清维生素D水平。耐心。方法：对36例日本患者的48个连续AFF进行回顾性分析，包括9例25-羟基维生素D（25（OH）D）水平的9例（AFF组）。研究。作为非AFF对照组，纳入了45例年龄相匹配的女性骨质疏松症患者（骨质疏松症组）。我们比较了一些实验室检查项目，骨矿物质密度和股骨曲率。结果：当进行单因素逻辑回归分析以比较两组时，AFF组的钙水平以及侧弯和前弯均显着高于骨质疏松症组（分别为P <0.05，P <0.01和P <0.01） ，AFF组的25（OH）D水平显着低于骨质疏松症组（P <0.01）。我们对这些提取物进行了判别分析，以排除因素之间的相互影响，并确定与AFF密切相关的因素，并且25（OH）D，Ca和前曲率被认为是区分这些疾病的重要因素（P <0.05，P < 0.01和P <0.01）。结论：AFF患者维生素D水平低，股骨弯曲明显。

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