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Osteosarcoma of Mandible: Report of Two Cases with Review of Literature

机译:下颌骨肉瘤:两例报告并文献复习

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Primary neoplasms of human skeleton are rare, accountingfor 0.2% of overall human tumor burden. Osteosarcoma (OS)accounts for 15 to 35% of all primary bone tumors, in jaw bones,it is even, rarer representing 4 to 8% of all os . Peak incidencefor jaw os is in 3rd to 4th decades while in long bones, it showsa bimodal age distribution. It may occur inside the bones (in theintramedullary or intracortical compartment), on the surfacesof bones and in extraosseous sites. Dental professionals maybe first to detect jaw os in their initial stages. Regardless ofthe favorable biologic behavior, the patients of jaw os usuallyexhibit advanced tumor as it often goes unnoticed thus it isimportant for early diagnosing this lesion. Here, we report2 cases of os with different histological subtypes (chrondroblasticand osteoblastic) and review of literature.
机译:人体骨骼的原发性肿瘤很罕见,占人类整体肿瘤负担的0.2%。骨肉瘤(OS)占所有原发性骨肿瘤的15%至35%,在颌骨中更为罕见,占所有os的4%至8%。下颌骨的发病率峰值出现在第3至第4个十年,而在长骨中,它表现出双峰年龄分布。它可能发生在骨骼内部(髓内或皮质内腔),骨骼表面和骨外部位。牙科专业人员可能会在最初阶段首先检测下颌骨。不管生物学行为如何,下颌骨患者通常都会表现出晚期肿瘤,因为它常常被忽视,因此对于早期诊断该病变很重要。在这里,我们报告2例不同组织学亚型(长韧体和成骨细胞)的os并文献复习。

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