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首页> 外文期刊>Orthopaedic Journal of Sports Medicine >Effect of Preoperative Gabapentin With a Concomitant Adductor Canal Block on Pain and Opioid Usage After Anterior Cruciate Ligament Reconstruction
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Effect of Preoperative Gabapentin With a Concomitant Adductor Canal Block on Pain and Opioid Usage After Anterior Cruciate Ligament Reconstruction

机译：术前加巴喷丁并用引流管阻滞对前交叉韧带重建术后疼痛和阿片类药物使用的影响

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Background: An adductor canal block (ACB) and preoperative oral gabapentin have each been shown to decrease postoperative pain scores and opioid usage in patients undergoing anterior cruciate ligament (ACL) reconstruction. Purpose/Hypothesis: This study evaluated the efficacy of preoperative gabapentin on postoperative analgesia in patients who received an ACB. We hypothesized that patients undergoing ACL reconstruction with an ACB who utilized a single dose of preoperative oral gabapentin would have decreased pain and opioid consumption in the 24 to 72 hours after surgery compared with patients who did not utilize gabapentin. Study Design: Cohort study; Level of evidence, 3. Methods: Between January and October 2016, patients at a single institution who underwent ACL reconstruction and received an ACB were identified. Patients who underwent surgery before May 2016 were placed in the control group, and patients seen after May 2016 received a preoperative dose of gabapentin and were placed in the gabapentin group. All patients completed a pain log via a smartphone application to record pain scores and opioid usage after surgery. Results: A total of 74 patients were identified: 41 in the gabapentin group and 33 in the control group. There were no significant differences between groups in demographics and operative characteristics. There were no differences in pain scores on postoperative day 1 (gabapentin vs control: 5.53 vs 5.56; P = .95), day 2 (4.58 vs 4.83; P = .59), or day 3 (4.15 vs 3.87; P = .59). The mean opioid consumption in oral morphine equivalents was not different on postoperative day 1 (gabapentin vs control: 47.2 vs 48.1; P = .90), day 2 (29.9 vs 33.5; P = .60), or day 3 (17.4 vs 18.7; P = .80). Conclusion: Preoperative gabapentin did not reduce pain scores or opioid usage in patients who received an ACB and underwent ACL reconstruction in this retrospective cohort study.
机译：背景：前交叉韧带（ACL）重建患者的内收管阻滞（ACB）和术前口服加巴喷丁均降低术后疼痛评分和阿片类药物使用。目的/假设：本研究评估了接受ACB的患者术前加巴喷丁对术后镇痛的疗效。我们假设使用ACB进行ACL重建的患者，与未使用加巴喷丁的患者相比，术前口服单剂量加巴喷丁的患者在术后24至72小时内疼痛和阿片类药物的消耗量将减少。研究设计：队列研究;证据等级，3。方法：在2016年1月至2016年10月之间，识别出接受单一ACL重建并接受ACB的患者。将2016年5月之前接受手术的患者放入对照组，而2016年5月之后看过的患者接受术前加巴喷丁治疗，并放入加巴喷丁治疗组。所有患者均通过智能手机应用程序完成了疼痛记录，以记录手术后的疼痛评分和阿片类药物的使用情况。结果：共鉴定出74例患者：加巴喷丁组41例，对照组33例。两组在人口统计学和手术特征方面无显着差异。术后第1天（加巴喷丁vs对照：5.53 vs 5.56; P = .95），第2天（4.58 vs 4.83; P = 0.59）或第3天（4.15 vs 3.87; P =。 59）。术后第1天，口服吗啡当量的平均阿片类药物摄入量无差异（加巴喷丁vs对照：47.2 vs 48.1; P = 0.90），第2天（29.9 vs 33.5; P = 0.60）或第3天（17.4 vs 18.7） ; P = .80）。结论：在这项回顾性队列研究中，术前加巴喷丁未降低接受ACB并接受ACL重建的患者的疼痛评分或阿片类药物使用量。

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