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首页> 外文期刊>SAHARA-J >Longitudinal analysis of HIV risk behaviour patterns and their predictors among public primary care patients with tuberculosis in South Africa
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Longitudinal analysis of HIV risk behaviour patterns and their predictors among public primary care patients with tuberculosis in South Africa

机译：南非结核病公共初级保健患者中HIV风险行为模式及其预测因素的纵向分析

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The goal of this study was to identify various HIV risk behaviours among tuberculosis (TB) patients in a longitudinal study design in South Africa. In 42 public primary healthcare facilities in three districts in three provinces, adult new TB and TB retreatment patients with hazardous or harmful alcohol use were interviewed within 1 month of initiation of anti-TB treatment and were followed up at 6 months. The total sample with a complete 6-month follow-up assessment was 853. At the follow-up assessment, several HIV risk behaviours significantly reduced from baseline to follow-up. In multivariate Generalized Estimating Equations logistic regression analyses, high poverty (odds ratio (OR): 2.68, 95% confidence interval (CI): 1.56–4.62), Posttraumatic Stress Disorder (PTSD) symptoms (OR?=?1.55, 95% CI?=?1.03–2.36), and sexual partner on antiretroviral therapy (ART) (OR?=?1.84, 95% CI?=?1.09–3.10) were associated with a higher odds, and excellent/very good perceived health status (OR: 0.61, 95% CI: 0.37–0.98), severe psychological stress (OR?=?0.51, 95% CI?=?0.34–0.77), and HIV non-disclosure to most recent sexual partner (OR?=?0.40, 95% CI?=?0.25–0.65) were associated with a lower odds of inconsistent condom use. Being HIV positive (OR?=?4.18, 95% CI?=?2.68–6.53) and excellent/very subjective health status (OR?=?2.98, 95% CI?=?1.73–5.13) were associated with a higher odds, and having PTSD symptoms (OR?=?0.60, 95% CI?=?0.36–0.99), being on ART (OR?=?0.48, 95% CI?=?0.25–0.95), having a sexual partner on ART (OR?=?0.41, 95% CI?=?0.18–0.96), and HIV status non-disclosure (OR?=?0.25, 95% CI?=?0.15–0.41) were associated with a lower odds of having sex with an HIV-positive or HIV status unknown person. High poverty index (OR?=?1.97, 95% CI?=?1.19–3.25) and having a sexual partner on ART (OR?=?4.37, 95% CI?=?1.82–10.48) were associated with a higher odds, and having a partner with HIV-negative status (OR?=?0.29, 95% CI?=?0.16–0.51) and inconsistent condom use (OR?=?0.39, 95% CI?=?0.24–0.64) were associated with a lower odds of HIV status non-disclosure at last sex. The study found that among TB patients with problem drinking over a 6-month TB treatment period, the frequency of some HIV risk behaviours (inconsistent condom use) declined (OR?=?0.64, 95% CI?=?0.41–0.98), but also persisted at a high-level calling for a strengthening and integration of HIV prevention into TB management.
机译：这项研究的目的是在南非的一项纵向研究设计中确定结核病患者中的各种HIV危险行为。在三个省的三个地区的42个公共基层医疗机构中，在开始抗结核治疗后的1个月内接受了成年新的结核病患者和有害或有害饮酒的结核病再治疗患者的随访，并在6个月后进行了随访。进行了为期6个月的完整跟踪评估的总样本为853。在跟踪评估中，从基线到跟踪随访，明显减少了几种HIV风险行为。在多变量广义估计方程的逻辑回归分析中，高贫困（优势比（OR）：2.68，95％置信区间（CI）：1.56-4.62），创伤后应激障碍（PTSD）症状（OR？=？1.55，95％CI ？=？1.03–2.36）和抗逆转录病毒疗法（ART）的性伴侣（OR？=？1.84，95％CI？=？1.09–3.10）与较高的几率和良好/非常好的感知健康状况相关（ OR：0.61，95％CI：0.37-0.98），严重的心理压力（OR？=？0.51，95％CI？=？0.34-0.77），以及未向最近的性伴侣透露HIV（OR？=？0.40） ，95％CI？=？0.25-0.65）与使用安全套不一致的几率更低。 HIV阳性（OR？=？4.18，95％CI？=？2.68–6.53）和良好/非常主观的健康状况（OR？=？2.98，95％CI？=？1.73-5.13）与更高的几率相关，并且患有PTSD症状（OR？=？0.60，95％CI？=？0.36-0.99），正在接受ART（OR？=？0.48，95％CI？=？0.25-0.95），并且在ART上有性伴侣（OR？=？0.41，95％CI？=？0.18–0.96）和未公开HIV状况（OR？=？0.25，95％CI？=？0.15–0.41）与发生性行为的几率较低相关HIV阳性或HIV状况未知的人。高贫困指数（OR == 1.97，95％CI == 1.19–3.25）和在ART上有性伴侣（OR == 4.37，95％CI == 1.82-10.48）与较高的几率相关，并且伴有艾滋病毒呈阴性状态的伴侣（OR？=？0.29，95％CI？=？0.16-0.51）和使用安全套不一致（OR？=？0.39，95％CI？=？0.24-0.64）最后一次性交时未透露HIV状况的几率较低。研究发现，在经过6个月的结核病治疗期间有饮酒问题的结核病患者中，某些HIV危险行为（使用安全套不一致）的频率有所下降（OR = 0.64，95％CI = 0.41-0.98），但也始终坚持高级别呼吁，要求将艾滋病毒的预防工作加强和纳入结核病管理。

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