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首页> 外文期刊>Sao Paulo Medical Journal >A study of the pharmacological actions of Dioclea grandiflora martius ex bentham
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A study of the pharmacological actions of Dioclea grandiflora martius ex bentham

机译:宾汉(Dientlea)的马鞭草(Dioclea grandiflora martius ex bentham)的药理作用研究

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Dioclea grandiflora Mart. ex Bent., known as Mucuna or Mucuna of stone, is a member of the Leguminosae family, popularly used for its possible effects on the Central Nervous System (CNS). Reports mention sedative, tonic, and also antiepileptic properties for this plant. In this paper a screening for CNS action was done with aqueous extracts of the seeds. This study was carried out using some animal models for the study of sedative, hypnotic, anxiolytic, anticonvulsivant and neuroleptic activity. The results showed that Dioclea grandiflora Mart. ex Bent. demonstrates the general profile of a CNS depressant drug. However, the extract did not exhibit any of the specific profiles tested. Moreover, the results suggest a possible toxicity stemming from the popular or folk use of this plant.
机译:大花的Dioclea大花市场。 ex Bent。是豆科植物的成员,被称为豆科豆或石头科豆科,因其对中枢神经系统(CNS)的可能作用而被广泛使用。报告提到了该植物的镇静,滋补和抗癫痫特性。在本文中,使用种子的水提物进行了CNS作用的筛选。该研究是使用一些动物模型进行的,以研究其镇静,催眠,抗焦虑,抗惊厥和抗精神病药的活性。结果表明,大丁香的是大叶菊。前弯。证明了中枢神经系统抑制药的概况。但是,提取物没有表现出任何测试的具体特征。此外,结果表明该植物的流行或民间使用可能引起毒性。

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