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首页> 外文期刊>Sao Paulo Medical Journal >Characteristics of ascitic fluid from patients with suspected spontaneous bacterial peritonitis in emergency units at a tertiary hospital
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Characteristics of ascitic fluid from patients with suspected spontaneous bacterial peritonitis in emergency units at a tertiary hospital

机译:三级医院急诊科怀疑自发性细菌性腹膜炎患者的腹水特征

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CONTEXT AND OBJECTIVE: Spontaneous bacterial peritonitis (SBP) is a complication of ascites, especially in cirrhosis. Ascitic fluid with 250 or more neutrophils/mm3 is an acceptable criterion for diagnosis, even when bacterial fluid cultures are negative. The aims here were to estimate SBP frequency among emergency room patients based on cellular criteria and evaluate the biochemical profile of these fluids. DESIGN AND SETTING: Retrospective study at a public tertiary hospital. METHODS: Laboratory records of patients with ascites attended in emergency rooms between November 2001 and November 2006, from whom ascitic fluid samples were sent to the laboratory due to suspected SBP, were evaluated. The 691 samples included were divided into group A (presumed SBP: 250 neutrophils/mm3; n = 219; 31.7%) and group B (no presumed SBP: < 250 neutrophils/mm3; n = 472; 68.3%). Patients' sex and age; ascitic fluid characteristics (numbers of neutrophils, leukocytes and nucleated cells); bacteriological characteristics; and protein, lactate dehydrogenase, adenosine deaminase and glucose concentrations were evaluated. RESULTS: Among group A cultured samples, 63 (33.8%) had positive bacterial cultures with growth of pathogens commonly associated with SBP. In total, the group A samples showed higher lactate dehydrogenase levels than seen in the group B samples. The latter presented predominance of lymphocytes and macrophages. CONCLUSION: Among the ascitic fluid samples with clinically suspected SBP, 31.7% fulfilled the cellular diagnostic criteria. Positive bacterial isolation was found in 33.8% of the cultured samples from the presumed SBP group
机译:背景与目的:自发性细菌性腹膜炎(SBP)是腹水的并发症,尤其是在肝硬化中。嗜中性粒细胞为250或更多/ mm3的腹水是诊断的可接受标准,即使细菌液培养阴性。此处的目的是根据细胞标准评估急诊室患者的SBP频率,并评估这些液体的生化特性。设计与设置:在公立三级医院进行回顾性研究。方法:对2001年11月至2006年11月期间在急诊室就诊的腹水患者的实验室记录进行了评估,由于怀疑是SBP而将腹水样本送至实验室。包括的691个样本分为A组(假定SBP:> 250中性粒细胞/ mm3; n = 219; 31.7%)和B组(未假定SBP:<250中性粒细胞/ mm3; n = 472; 68.3%)。患者的性别和年龄;腹水特征(中性粒细胞,白细胞和有核细胞的数量);细菌学特征并评估蛋白质,乳酸脱氢酶,腺苷脱氨酶和葡萄糖浓度。结果:在A组培养的样本中,有63份(33.8%)的细菌培养呈阳性,且病原菌通常与SBP相关。总体而言,A组样品显示的乳酸脱氢酶水平高于B组样品。后者主要表现为淋巴细胞和巨噬细胞。结论:在临床怀疑为SBP的腹水样本中,有31.7%符合细胞诊断标准。假定的SBP组中有33.8%的培养样品中发现细菌分离阳性

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