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首页> 外文期刊>Sao Paulo Medical Journal >Patent blue and air as an alternative for resection of nonpalpable breast lesions: a case series
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Patent blue and air as an alternative for resection of nonpalpable breast lesions: a case series

机译：专利蓝色和空气替代切除不可触及的乳腺病变的病例系列

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CONTEXT AND OBJECTIVE: Use of mammography for breast cancer screening has resulted in a significantly increased number of patients with nonpalpable radiological findings that need histopathological study for better management. The present study evaluated an alternative to excision of nonpalpable breast lesions, using injection of patent blue (CAS 3536-49-0) dye and air. DESIGN AND SETTING: Cohort study of 64 consecutive patients at a private clinic in the city of Teresina (Piauí), between January 2009 and December 2010. METHODS : The patients had received mammographic diagnoses of nonpalpable breast lesions classified as BI-RADS 3, 4 and 5, with indication of histopathological study. They underwent stereotaxy and/or ultrasound-guided injection of patent blue, for marking and subsequent excision of the lesion. RESULTS : The patients' mean age was 47.7 years. Nodes accounted for 53.1% of the breast abnormalities; microcalcifications, 37.5%; and complex cysts, 9.4%. In 89.1% of cases, the lesions were BI-RADS 4; 7.8% were BI-RADS 5 and 3.1% were BI-RADS 3. The histopathological findings were benign in 70.3% of the cases; atypical hyperplasia, 9.4%; and malignant, 20.3%. Among the malignant cases, 53.8% were carcinoma in situ and 46.2%, invasive carcinoma. The percentage of malignancy was 0% in BI-RADS 3 lesions; 14.3% in BI-RADS 4 and 100% in BI-RADS 5. In the cases of malignancy, the margins were clear in 92.3%. Reoperation to widen the margins was required in one patient. CONCLUSION: Excision of nonpalpable breast lesions marked with patent blue and air was possible in all cases.
机译：背景与目的：乳房X线照相术用于乳腺癌筛查的结果是，显着增加需要影像学检查以进行更好管理的放射学检查结果的患者数量大大增加。本研究评估了一种不可触及的乳房病变切除术的替代方法，方法是使用专利蓝色（CAS 3536-49-0）染料和空气进行注射。设计与地点：2009年1月至2010年12月，在Teresina市（Piauí）的一家私人诊所对64位连续患者进行的队列研究。方法：患者接受了X线检查，诊断为无法触及的乳腺病变，分类为BI-RADS 3、4和5，具有组织病理学研究的迹象。他们进行了立体定位和/或超声引导下的蓝色专利注射，以标记和随后切除病灶。结果：患者的平均年龄为47.7岁。淋巴结占乳腺异常的53.1％;微钙化，37.5％;和复杂的囊肿，占9.4％。在89.1％的病例中，病灶为BI-RADS 4; BI-RADS 5为7.8％，BI-RADS 3为3.1％。在70.3％的病例中，组织病理学检查结果是良性的。非典型增生，9.4％;和恶性的20.3％。在恶性病例中，原位癌为53.8％，浸润性癌为46.2％。 BI-RADS 3病变的恶性百分比为0％;在BI-RADS 4中为14.3％，在BI-RADS 5中为100％。在恶性肿瘤的情况下，清除率达到了92.3％。一名患者需要再次手术以扩大切缘。结论：在所有情况下都可以切除未触及的乳腺，并标有漆蓝色和空气。

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