• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sao Paulo Medical Journal >Longitudinal assessment of the lung mechanics of very low birth weight preterm infants with and without bronchopulmonary dysplasia
【24h】

Longitudinal assessment of the lung mechanics of very low birth weight preterm infants with and without bronchopulmonary dysplasia

机译：极低出生体重早产儿有或没有支气管肺发育不良的肺力学的纵向评估

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT CONTEXT AND OBJECTIVE: Prematurity has been correlated with altered lung mechanics. Some infants develop lung injury as a consequence of lung immaturity, invasive mechanical ventilation and exposure to oxygen, thus resulting in bronchopulmonary dysplasia. The aim here was to compare the lung mechanics of preterm infants with and without bronchopulmonary dysplasia during the first year of life. DESIGN AND SETTING: Prospective cohort study in a tertiary-level hospital. METHODS: This study included premature infants at a public hospital who underwent two pulmonary function tests: one at discharge and the other at the corrected age of 4 to 8 months. Tidal volume, lung compliance and lung resistance were measured. Statistical tests were used for comparisons between infants with and without bronchopulmonary dysplasia. RESULTS: 102 children with mean gestational age of 29 ± 2.0 weeks were studied; 17 with bronchopulmonary dysplasia. Lung compliance (0.84 ± 0.29 versus 1.28 ± 0.46; P 0.001) and tidal volume (6.1 ± 0.94 versus 7.2 ± 1.43; P 0.01) at discharge were significant lower in children with bronchopulmonary dysplasia than in those without the disease, but no differences were observed at the second test (compliance: 1.53 ± 0.77 versus 1.94 ± 1.01; P = 0.12; and tidal volume: 6.9 ± 1.4 versus 7.3 ± 1.6; P = 0.42). CONCLUSION: Differences in lung mechanics were observed between infants with and without bronchopulmonary dysplasia at hospital discharge but these differences were no longer detected at the final follow-up. The lung mechanics of all the infants improved over this period of time.
机译：摘要背景和目的：早产与肺力学改变有关。一些婴儿由于肺不成熟，有创机械通气和暴露于氧气而导致肺损伤，从而导致支气管肺发育不良。目的是比较出生后第一年有和没有支气管肺发育不良的早产儿的肺力学。设计与地点：在三级医院进行的前瞻性队列研究。方法：本研究包括一家公立医院的早产儿，他们接受了两项肺功能检查：一项在出院时进行，另一项在4至8个月的校正年龄下进行。测量潮气量，肺顺应性和肺阻力。统计测试用于比较有无支气管肺发育不良的婴儿。结果：对102名平均胎龄为29±2.0周的儿童进行了研究。 17例伴有支气管肺发育不良。患有支气管肺发育不良的儿童出院时的肺顺应性（0.84±0.29对1.28±0.46; P <0.001）和潮气量（6.1±0.94对7.2±1.43; P <0.01）显着低于无疾病的儿童，但无在第二次测试中观察到差异（顺应性：1.53±0.77对1.94±1.01; P = 0.12;潮气量：6.9±1.4对7.3±1.6; P = 0.42）。结论：出院时有和没有支气管肺发育不良的婴儿在肺力学方面存在差异，但在最后的随访中不再发现这些差异。在这段时间里，所有婴儿的肺力学都得到了改善。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号