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首页> 外文期刊>Sao Paulo Medical Journal >Beh?et's syndrome / AIDS / cerebral toxoplasmosis: an unusual association
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Beh?et's syndrome / AIDS / cerebral toxoplasmosis: an unusual association

机译：贝赫特氏综合症/艾滋病/脑弓形体病：一种不寻常的关联

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Few cases of AIDS associated to manifestations suggesting Beh?et's syndrome have been reported. This case is of a young married woman who presented, during a period of 7 years, clinical manifestations consistent with the late diagnosis of Beh?et's syndrome, when she developed recurrent lymphomonocytic meningoencephalitis. At this time, she was found to be infected by HIV-1. Immunosupressive doses of glucocorticoid produced an unsatisfactory response and she evolved to death due to CNS toxoplasmosis. The latter diagnosis was presumed on the basis of magnetic resonance imaging findings and proved by necropsy after her third hospital stay. One of the factors hindering the appropriate diagnosis was the low level of CD4 and the CD4/CD8 ratio, sometimes observed in active Beh?et's syndrome and higher than those observed in patients with this severe opportunistic infection. No information about the exact period of time she had been infected with HIV-1 is available. So, we do not know whether both diseases were overlor, if the patient, infected by HIV-1, developed an unusual clinical feature consistent with Beh?et's Beh?et's syndrome, and subsequently evolved to AIDS.
机译：很少有艾滋病病例与暗示贝氏综合征的表现有关。这个病例是一个年轻的已婚妇女，她在7年内出现复发性淋巴细胞单核细胞性脑膜炎时，表现出与贝赫特氏综合征的晚期诊断相一致的临床表现。这时，她被发现感染了HIV-1。免疫抑制剂量的糖皮质激素产生不令人满意的反应，并且由于中枢神经系统弓形虫病而演变成死亡。后者的诊断是根据磁共振成像发现推测的，并在她第三次住院后通过尸检证实。阻碍适当诊断的因素之一是CD4和CD4 / CD8比率低，有时在活动性贝氏综合征中观察到，而在这种严重机会性感染患者中观察到则较高。没有关于她感染HIV-1确切时间的信息。因此，我们不知道这两种疾病是否都是总的，如果该患者被HIV-1感染，是否出现了与贝赫特氏贝赫特氏综合征一致的异常临床特征，然后演变为艾滋病。

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