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Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study

机译:外阴细胞性血管纤维瘤:临床病理和免疫组织化学研究的病例报告

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CONTEXT: Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins. CASE REPORT: We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.
机译:语境:外阴细胞性血管纤维瘤是一种罕见的肿瘤,于1997年首次被描述。它发生于中年妇女(平均年龄:47岁),体形小(<3 cm),边界清楚。病例报告:我们描述了一名51岁女性的病例,该女性的术前诊断与Bartholin的腺囊肿相混淆。赘生物界限清楚,由三个特征组成:形成小束的梭状细胞,大量血管和脂肪组织散布在梭状细胞之间。基质细胞的波形蛋白阳性,而CD34,蛋白S-100,肌动蛋白和结蛋白阴性。该肿瘤的鉴别诊断包括侵袭性血管平滑肌瘤,血管肌纤维母细胞瘤,梭形细胞脂肪瘤,孤立性纤维性肿瘤,神经鞘瘤和平滑肌瘤。

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