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Liver abscess in children: A 10-year single centre experience

机译:儿童肝脓肿:10年单中心经验

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Background/Aim: Although liver abscess is more prevalent in developing countries than in developed countries, there is scant data about the characteristics of pediatric liver abscess in our region. We aimed to analyze the characteristics of pediatric liver abscess in our region and compare these with those of developed countries. Materials and Methods: The clinical features, laboratory, imaging, microbiologic findings, management strategy, and final outcome were extracted from the patients' records retrospectively. Results: There were 18 cases of liver abscess including 16 pyogenic liver abscess, one amebic liver abscess and one candida liver abscess. Fever and abdominal pain were the most common clinical findings and leukocytosis was the most common laboratory finding. The most predisposing factors of liver abscess were immune deficiency, minor thalassemia. Origin of liver abscess was appendicitis in two patients, the rest were considered as cryptogenic. While one patient was treated with antibiotics alone, five cases were taken for open drainage, and 12 cases were treated with percutaneous aspiration. Percutaneous aspiration failed in two patients who were later ttaken for open drainage, with an overall mortality rate of 5.5%. Conclusion: The overall characteristics of liver abscess in children in our society are not so different from developed countries. However, in contradiction to cases reported in developed countries, most cases of liver abscess were seen in healthy patients in our centre. Moreover, liver abscess was reported in our patients at a younger age and was more commonly seen in male children. Mortality rate was similar to that of developed countries.
机译:背景/目的:尽管发展中国家的肝脓肿比发达国家更为普遍,但是关于我们地区小儿肝脓肿的特征的数据很少。我们旨在分析本地区小儿肝脓肿的特征,并将其与发达国家进行比较。材料和方法:回顾性地从患者记录中提取临床特征,实验室检查,影像学,微生物学发现,治疗策略和最终结果。结果:肝脓肿18例,其中化脓性肝脓肿16例,阿米巴肝脓肿1例,念珠菌肝脓肿1例。发烧和腹痛是最常见的临床发现,白细胞增多是最常见的实验室发现。肝脓肿的最易患因素是免疫缺陷,轻度地中海贫血。肝脓肿的起源是两名患者的阑尾炎,其余被认为是隐源性的。 1名患者仅接受抗生素治疗,5例行开放性引流,12例行经皮穿刺。两名患者的经皮穿刺抽吸失败,后来被开腹引流,总死亡率为5.5%。结论:我们社会儿童肝脓肿的总体特征与发达国家没有太大差异。但是,与发达国家报告的病例相反,在我们中心的健康患者中发现了大多数肝脓肿病例。此外,在我们的患者中报告了肝脓肿的年龄较小,在男孩中更为常见。死亡率与发达国家相似。

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