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首页> 外文期刊>Sao Paulo Medical Journal >Prevalence of prediabetes in patients with metabolic risk
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Prevalence of prediabetes in patients with metabolic risk

机译：具有代谢风险的患者中的糖尿病前期患病率

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CONTEXT AND OBJECTIVE: Early diagnosis of prediabetes should be done to avoid complications relating to diabetes mellitus (DM). The aim here was to assess the prevalence of prediabetes among individuals at high risk of developing DM, and to seek variables relating to glucose intolerance (GI) among individuals with normal fasting plasma glucose (FPG). DESIGN AND SETTING: Cross-sectional study at Hospital do Servidor Público Estadual, S?o Paulo. METHODS: The FPG and glucose tolerance test (GTT) were analyzed, from which the subjects were divided as follows: group 1 (FPG and GTT both normal), group 2 (normal FPG but abnormal GTT), group 3 (abnormal FPG but normal GTT), and group 4 (FPG and GTT both abnormal). The subjects' clinical, laboratory and anthropometric profile was determined. RESULTS: 138 subjects were studied: 44 in group 1, 11 in group 2, 33 in group 3 and 50 in group 4. The prevalence of prediabetes was 68.0%. Group 4 individuals were older than group 1 individuals [69.0 (55.5-74.0) versus 58.9 ± 11.8 years; P < 0.05], with greater prevalence of risk conditions for DM [5.0 (4.0-5.0) versus 4.0 (3.0-5.0); P < 0.05]. Among individuals with normal FPG, GI prevalence was 20.0%. No variables analyzed correlated with GTT. CONCLUSION: The prevalence of prediabetes was 68.0%, and 20.0% of subjects with normal FPG had GI. Although some anthropometric, clinical and laboratory variables have been correlated with DM and prediabetes, none, except for GTT, was able to screen for GI among subjects with normal FPG in the present study
机译：背景与目的：应尽早诊断糖尿病前期，以避免与糖尿病（DM）有关的并发症。此处的目的是评估罹患DM的高风险人群中的前驱糖尿病患病率，并在空腹血糖正常（FPG）的人群中寻找与葡萄糖耐量（GI）相关的变量。设计与环境：在圣保罗医院的ServidorPúblicoEstadual医院进行横断面研究。方法：分析了FPG和葡萄糖耐量测试（GTT），将受试者分为以下几组：第1组（FPG和GTT均正常），第2组（FPG正常但GTT异常），第3组（FPG异常但正常） GTT）和第4组（FPG和GTT均异常）。确定受试者的临床，实验室和人体测量学特征。结果：138名受试者进行了研究：第1组为44，第2组为11，第3组为33，第4组为50。前驱糖尿病的患病率为68.0％。第4组的年龄比第1组的年龄大[69.0（55.5-74.0）岁，相比58.9±11.8岁; P <0.05]，糖尿病的患病率更高[5.0（4.0-5.0）对4.0（3.0-5.0）; P <0.05]。在FPG正常的个体中，胃肠道患病率为20.0％。没有分析的变量与GTT相关。结论：糖尿病前期患病率为68.0％，FPG正常的受试者有GI。尽管一些人体测量学，临床和实验室变量已与DM和糖尿病前期相关，但在本研究中，除GTT外，没有一个能够筛查FPG正常受试者的GI。

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