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首页> 外文期刊>Sao Paulo Medical Journal >What do Cochrane systematic reviews say about cardiac arrest management?
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What do Cochrane systematic reviews say about cardiac arrest management?

机译:Cochrane系统评价对心脏骤停管理有何看法?

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ABSTRACT CONTEXT AND OBJECTIVE: Cardiac arrest is associated with high morbidity and mortality and imposes a significant burden on the healthcare system. Management of cardiac arrest patients is complex and involves approaches with multiple interventions. Here, we aimed to summarize the available evidence regarding the interventions used in cardiac arrest cases. DESIGN AND SETTING: Review of systematic reviews (SRs), conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de S?o Paulo. METHODS: A systematic search was conducted to identify all Cochrane SRs that fulfilled the inclusion criteria. Titles and abstracts were screened by two authors. RESULTS: We included nine Cochrane SRs assessing compression techniques or devices (three SRs), defibrillation (two SRs) and other interventions (two SRs on hypothermia interventions, one on airway management and one on pharmacological intervention). The reviews included found qualities of evidence ranging from unknown to high, regarding the benefits of these interventions. CONCLUSION: This review included nine Cochrane systematic reviews that provided a diverse range of qualities of evidence (unknown to high) regarding interventions that are used in management of cardiac arrest. High-quality evidence was found by two systematic reviews as follows: (a) increased survival until hospital discharge with continuous compression, compared with interrupted chest compression, both administered by an untrained person and (b) no difference regarding the return of spontaneous circulation, comparing aminophylline and placebo, for bradyasystolic patients under cardiac arrest. Further studies are needed in order to reach solid conclusions.
机译:摘要背景和目的:心脏骤停与高发病率和高死亡率相关,并给医疗保健系统带来巨大负担。心脏骤停患者的管理很复杂,涉及多种干预措施。在这里,我们旨在总结有关在心脏骤停病例中使用的干预措施的可用证据。设计与环境:系统评价(SR),在圣保罗联邦大学Escola Paulista de Medicina的循证医学学科中进行。方法:进行了系统搜索,以确定所有符合纳入标准的Cochrane SR。标题和摘要由两名作者筛选。结果:我们包括九个Cochrane SR,评估压缩技术或设备(三个SR),除纤颤(两个SR)和其他干预措施(两个关于低温治疗的SR,一个关于气道管理的SR,一个关于药理干预的SR)。审查包括发现的有关这些干预措施益处的证据质量,从未知到高度不等。结论:本评价包括9项Cochrane系统评价,这些评价提供了有关用于心脏骤停管理的干预措施的多种证据质量(鲜为人知)。两项系统的审查发现了高质量的证据,如下所示:(a)与未经连续训练的胸外按压相比,连续受压的连续出院可增加直至出院的生存率;(b)自发循环的恢复无差异,比较氨茶碱和安慰剂,用于心脏骤停的收缩期患者。为了得出可靠的结论,还需要进一步的研究。

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