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首页> 外文期刊>Sao Paulo Medical Journal >Preval?ancia de infec?§?￡o por Helicobacter pylori em uma comunidade ind?-gena em S?￡o Paulo e fatores associados: estudo transversal
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Preval?ancia de infec?§?￡o por Helicobacter pylori em uma comunidade ind?-gena em S?￡o Paulo e fatores associados: estudo transversal

机译：在圣保罗的一个土著社区中幽门螺杆菌感染的患病率及相关因素：横断面研究

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CONTEXT AND OBJECTIVE: The prevalence of Helicobacter pylori infection is unevenly distributed among different populations. The aim here was to evaluate the factors associated with Helicobacter pylori infection among children up to five years of age living in a high-risk community. DESIGN AND SETTING: Cross-sectional study in an indigenous community of Guarani Mbya ethnicity, Tekoa Ytu and Tekoa Pyau villages, Jaragu?? district, city of S?￡o Paulo (SP), Brazil. METHODS: 74 children aged 0.4 to 4.9 years (mean 2.9 ?± 1.3 years; median 3.1), and 145 family members (86 siblings, 43 mothers and 16 fathers) were evaluated for Helicobacter pylori infection using the validated 13 C-urea breath test. Clinical and demographic data were collected. RESULTS: The prevalence was 8.3% among children aged 1-2 years and reached 64.3% among those aged 4-5 years (P = 0.018; overall 31.1%). The prevalence was 76.7% among siblings and 89.8% among parents. There was a negative association with previous use of antibiotics in multivariate analysis adjusted for age (odds ratio, OR: 0.07; 95% confidence interval, CI: 0.01 to 0.66; P = 0.02). The prevalence was higher among males (OR: 1.55), and was associated with maternal infection (OR: 1.81), infection of both parents (OR: 1.5), vomiting (OR: 1.28), intestinal parasitosis (OR: 2.25), previous hospitalization (OR: 0.69) and breastfeeding (OR: 1.87). CONCLUSIONS: The prevalence was high among subjects older than three years of age, thus suggesting that the incidence of infection was higher over the first three years of life. Previous use of antibiotics was inversely associated with current Helicobacter pylori infection.
机译：背景与目的：幽门螺杆菌感染的流行在不同人群中分布不均。此处的目的是评估生活在高风险社区中的5岁以下儿童与幽门螺杆菌感染相关的因素。设计与环境：横断面研究在瓜拉尼姆比亚（Juangu）Tekoa Ytu和Tekoa Pyau村庄的土著社区进行？巴西圣保罗市（SP）市。方法：对74名0.4至4.9岁的儿童（平均2.9±1.3岁;中位3.1岁）和145名家庭成员（86名兄弟姐妹，43名母亲和16名父亲）进行了13 C-尿素呼气试验评估是否患有幽门螺杆菌感染。 。收集临床和人口统计学数据。结果：1-2岁儿童的患病率为8.3％，而4-5岁儿童的患病率为64.3％（P = 0.018;总体31.1％）。兄弟姐妹患病率为76.7％，父母患病率为89.8％。经年龄校正的多元分析与以前使用抗生素呈负相关（比值比，OR：0.07; 95％置信区间，CI：0.01至0.66; P = 0.02）。男性患病率较高（OR：1.55），与母亲感染（OR：1.81），父母双方感染（OR：1.5），呕吐（OR：1.28），肠道寄生虫病（OR：2.25）有关。住院（OR：0.69）和母乳喂养（OR：1.87）。结论：三岁以上的受试者患病率很高，因此表明在生命的头三年中感染的发生率较高。先前使用抗生素与当前的幽门螺杆菌感染呈负相关。

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