The rebound effect in the treatment of complex hemangioma with interferon alpha 2A

Guido Faiwichow; Jaime Anger; José Manoel Ernesto; José Pinus; Ricardo Gama Carneiro

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The rebound effect in the treatment of complex hemangioma with interferon alpha 2A

机译：干扰素α2A治疗复杂血管瘤的反弹作用

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The authors report the case of an infant with an extensive face hemangioma with subglottic airway obstruction which had been successfully treated with interferon alpha 2A but then reoccurred with the same dimensions and airway blockage after treatment was abruptly interrupted. The authors suggest the implementation of a standard procedure for the interruption of interferon alpha 2A treatment in order to avoid this rebound effect and advise on the need for further studies to properly evaluate dosage and administration parameters for interferon alpha 2A in the treatment of difficult hemangioma.

机译：作者报告了一例患有声门下气道阻塞的广泛性面部血管瘤的婴儿，该婴儿已成功用干扰素α2A治疗，但随后突然复发，再次发生了相同尺寸的呼吸道阻塞。作者建议采用标准程序中断干扰素α2A的治疗，以避免这种反弹效应，并建议需要进行进一步研究，以正确评估难治性血管瘤治疗中干扰素α2A的剂量和给药参数。

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《Sao Paulo Medical Journal》 |1998年第5期|共3页
作者
Guido Faiwichow; Jaime Anger; José Manoel Ernesto; José Pinus; Ricardo Gama Carneiro;
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中图分类临床医学;
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2. Pegylated interferon {alpha}2a plus ribavirin versus pegylated interferon {alpha}2b plus ribavirin for the treatment of chronic hepatitis C in HIV-infected patients. [J] . Berenguer J, Gonzalez Garcia J, Lopez Aldeguer J The Journal of Antimicrobial Chemotherapy . 2009,第6期

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机译：聚乙二醇干扰素α2a与干扰素α2b加利巴韦林联用作为慢性丙型肝炎患者初始治疗的生活质量，工作效率和医疗资源利用的比较。
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5. Rebound Relationships: An Investigation of HIV-1 Rebound Dynamics and Host Immune Responses During Analytical Treatment Interruption [D] . Salantes, D. Brenda. 2018

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6. Interferon-alpha-2a for the treatment of complex hemangiomas of infancy and childhood. [O] . R R Ricketts, R M Hatley, B J Corden, 1994

机译：干扰素-α2a用于治疗婴儿期和儿童期复杂的血管瘤。
7. The rebound effect in the treatment of complex hemangioma with interferon alpha 2A [O] . Jaime Anger, Ricardo Gama Carneiro, José Pinus, 1998

机译：干扰素α2a治疗复杂血管瘤的反弹效应

The rebound effect in the treatment of complex hemangioma with interferon alpha 2A

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