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Infeccion cutanea por mycobacterium fortuitum

机译:分枝杆菌感染的皮肤

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Mycobacteria are aerobic, non-spore forming, gram positive, acid-fast bacilli, which affect skin, subcutaneous tissue,and other organs and systems. Mycobacterium fortuitum produces cellulitis, abscesses, papules-pustules, nodules andulcers with serosanguinolent, purulent material, and subcutaneous necrosis. A 61-year-old woman, presents a case oftwo months of evolution that begins with reddish grain from an insect sting. After immersion in the Mexican Sea, itworsens, increases in quantity, is blistered and has brownish secretion; Physical examination shows erythematous plaque,with punctate orifices with hematic and meliceric crusts; Pustules and satellite papules, on the anterior aspect of theright leg. Histopathology: Suppurative dermal granulomas, centered by acute leukocyte infiltrate, with liquefactivetissue necrosis, surrounded by chronic inflammation with macrophages, plasma cells, lymphocytes, multinucleatedgiant cells. The first skin culture returns negative; in the second skin culture, fast-growing, non-pigmented atypicalmycobacteria. Molecular detection is performed by Polymerase Chain Reaction: Mycobacterium fortuitum. Treatmentwith Ciprofloxacin 500 mg every 12 hours, with resolution of the table to the eighth month. A case of cutaneousinfection by Mycobacterium fortuitum, related to the immersion in the sea and corals, whose diagnostic process hasbeen difficult and was achieved by techniques of advanced molecular biology.
机译:分枝杆菌是需氧的,无芽孢的,革兰氏阳性的,耐酸的细菌,会影响皮肤,皮下组织以及其他器官和系统。福特分枝杆菌产生蜂窝组织炎,脓肿,丘疹丘疹,结节性溃疡和血清嗜血性,化脓性物质和皮下坏死。一名61岁的女性出现了两个月的进化案例,该案例以昆虫叮咬后的微红谷物开始。浸入墨西哥海后,变质,数量增加,起泡并且分泌物呈褐色。体格检查发现红斑,斑状孔口有血和硬皮结;右腿前部的脓疱和附属性丘疹。组织病理学:化脓性皮肤肉芽肿,以急性白细胞浸润为中心,液化组织坏死,周围为慢性炎症,周围有巨噬细胞,浆细胞,淋巴细胞,多核巨细胞。最初的皮肤文化恢复为阴性;在第二次皮肤培养中,快速生长,无色素的非典型分枝杆菌。分子检测通过聚合酶链反应:Fort分支杆菌进行。每12小时用环丙沙星500 mg进行治疗,治疗表的有效期为第八个月。一例因分枝杆菌引起的皮肤感染,与浸入海洋和珊瑚有关,其诊断过程很困难,并通过先进的分子生物学技术得以实现。

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