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The role of glycated hemoglobin (HbA1c) and serum lipid profile measurements to detect cardiovascular diseases in type 2 diabetic patients

机译:糖化血红蛋白(HbA1c)和血脂谱检测在2型糖尿病患者中检测心血管疾病的作用

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Patients with diabetes are considered to be at more risk of dyslipidemia and hypertension, hence targets for cardiovascular diseases. This study describes the possible role of Glycated Hemoglobin (HbA1c) and serum lipid profile as a biomarker in the detection of cardiovascular diseases. A cross-sectional study was carried out on 54 (33 males and 21 females) type 2 diabetes (T2DM) patients at Ayub Teaching Hospital (ATH), Abbottabad and Mardan Medical Complex (MMC), Mardan, Khyber Pukhtunkhwa (KP), Pakistan. The control group comprised of 20 (13 males and 7 females) healthy human samples. The patients had significantly higher ( p 7.0%, had higher TG than those with HbA1c≤7.0%. Furthermore, 14.2% patients with HbA1c>7.0% had cerebrovascular diseases and 28% have ischemic heart diseases. The findings of the current study suggests association of HbA1c with lipid profile in T2DM patients and both might be used as a predictor of cardiovascular diseases in such patients. South East Asia Journal of Public Health Vol.5(2) 2015: 30-34
机译:糖尿病患者被认为血脂异常和高血压的风险更高,因此是心血管疾病的目标。这项研究描述了糖化血红蛋白(HbA1c)和血脂谱作为检测心血管疾病的生物标志物的可能作用。在巴基斯坦阿伯塔巴德和马尔丹医学中心(MMC)的阿尤布教学医院(ATH),巴基斯坦开伯尔·普赫图赫瓦(Khyber Pukhtunkhwa)的马尔丹(Ayub教学医院)对54名(33名男性和21名女性)2型2型糖尿病(T2DM)患者进行了横断面研究。对照组包括20名(13名男性和7名女性)健康人类样品。与HbA1c≤7.0%的患者相比,患者明显更高(p 7.0%,TG更高。此外,HbA1c> 7.0%的患者中有14.2%的患者患有脑血管疾病,而缺血性心脏病的患者则占28%。 Tb2DM患者中具有血脂分布的HbA1c的水平,均可以作为此类患者心血管疾病的预测指标。东南亚公共卫生杂志,Vol.5(2)2015:30-34

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