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首页> 外文期刊>Standards in Genomic Sciences >Complete genome sequence of Corynebacterium pseudotuberculosis biovar ovis strain P54B96 isolated from antelope in South Africa obtained by rapid next generation sequencing technology
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Complete genome sequence of Corynebacterium pseudotuberculosis biovar ovis strain P54B96 isolated from antelope in South Africa obtained by rapid next generation sequencing technology

机译：下一代快速测序技术从南非羚羊分离得到假结核棒状杆菌Biovar ovis菌株P54B96的完整基因组序列

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摘要

The Actinobacteria, Corynebacterium pseudotuberculosis strain P54B96, a nonmotile, non-sporulating and a mesophile bacterium, was isolated from liver, lung and mediastinal lymph node lesions in an antelope from South Africa. This strain is interesting in the sense that it has been found together with non-tuberculous mycobacteria (NTMs) which could nevertheless play a role in the lesion formation. In this work, we describe a set of features of C. pseudotuberculosis P54B96, together with the details of the complete genome sequence and annotation. The genome comprises of 2.34 Mbp long, single circular genome with 2,084 protein-coding genes, 12 rRNA, 49 tRNA and 62 pseudogenes and a G+C content of 52.19%. The analysis of the genome sequence provides means to better understanding the molecular and genetic basis of virulence of this bacterium, enabling a detailed investigation of its pathogenesis.
机译：从南非羚羊的肝，肺和纵隔淋巴结病变中分离出一种不活动，不产芽和嗜温细菌的放线杆菌假结核杆菌菌株P54B96。从已经发现它与非结核分枝杆菌（NTM）在一起的意义上讲，该菌株很有趣，但它仍可在病变的形成中起作用。在这项工作中，我们描述了假单胞菌P54B96的一组功能，以及完整基因组序列和注释的详细信息。该基因组由2.34 Mbp长的单个环状基因组组成，具有2084个蛋白质编码基因，12个rRNA，49个tRNA和62个假基因，G + C含量为52.19％。基因组序列的分析提供了更好地了解这种细菌毒力的分子和遗传基础的手段，从而能够对其发病机理进行详细研究。

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