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首页> 外文期刊>Standards in Genomic Sciences >Complete genome sequence of Streptococcus agalactiae strain GBS85147 serotype of type Ia isolated from human oropharynx
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Complete genome sequence of Streptococcus agalactiae strain GBS85147 serotype of type Ia isolated from human oropharynx

机译：分离自人口咽的Ia型无乳链球菌菌株GBS85147血清型的完整基因组序列

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Streptococcus agalactiae , also referred to as Group B Streptococcus , is a frequent resident of the rectovaginal tract in humans, and a major cause of neonatal infection. The pathogen can also infect adults with underlying disease, particularly the elderly and immunocompromised ones. In addition, S. agalactiae is a known fish pathogen, which compromises food safety and represents a zoonotic hazard. This study provides valuable structural, functional and evolutionary genomic information of a human S. agalactiae serotype Ia (ST-103) GBS85147 strain isolated from the oropharynx of an adult patient from Rio de Janeiro, thereby representing the first human isolate in Brazil. We used the Ion Torrent PGM platform with the 200?bp fragment library sequencing kit. The sequencing generated 578,082,183?bp, distributed among 2,973,022 reads, resulting in an approximately 246-fold mean coverage depth and was assembled using the Mira Assembler v3.9.18. The S. agalactiae strain GBS85147 comprises of a circular chromosome with a final genome length of 1,996,151?bp containing 1,915 protein-coding genes, 18 rRNA, 63 tRNA, 2 pseudogenes and a G?+?C content of 35.48?%.
机译：无乳链球菌，也称为B组链球菌，是人类直肠阴道道的常见居民，是新生儿感染的主要原因。该病原体还可以感染具有潜在疾病的成年人，尤其是老年人和免疫功能低下的成年人。另外，无乳链球菌是已知的鱼类病原体，其危害食品安全并代表人畜共患病危害。这项研究提供了人类无乳链球菌血清型Ia（ST-103）GBS85147菌株的有价值的结构，功能和进化基因组信息，该菌株从里约热内卢的一名成年患者的口咽中分离出来，从而代表了巴西的第一个人类分离株。我们将Ion Torrent PGM平台与200？bp片段文库测序试剂盒一起使用。测序产生578,082,183？bp，分布在2,973,022个读段中，平均覆盖深度约为246倍，并使用Mira Assembler v3.9.18进行了组装。无乳链球菌菌株GBS85147包括一个环状染色体，其最终基因组长度为1,996,151？bp，包含1,915个蛋白质编码基因，18个rRNA，63个tRNA，2个假基因和G？+？C含量为35.48％。

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