...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sri Lanka Journal of Psychiatry >Efficacy of clozapine in patients with chronic schizophrenia
【24h】

Efficacy of clozapine in patients with chronic schizophrenia

机译：氯氮平对慢性精神分裂症患者的疗效

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Clozapine is the most effective treatment for refractory schizophrenia. There is evidence that clozapine improves social and occupational functioning and patients’ quality of life. Aims To evaluate the presence of psychopathology and level of functioning in a cohort of patients treated with clozapine. Methods Sixty seven patients attending a clozapine clinic during a two month period were enrolled. Sociodemographic characteristics, duration of treatment and dose of clozapine were recorded. Symptom severity was measured using a psychopathology scale. Level of functioning was assessed using the "Psycho Social Functioning Scale". Results Of the sample 53.7% were males. Majority were aged 20-39 years. In the sample 7.4% were treated with clozapine for two years or less, 38.8% for 3-5 years and 40.3% for 6-10 years. Of the sample 43.3% were on 225-400 mg/day. In the self care sub scale 61 (95.3%) scored 13-15 from a maximum of 15. In the daily function sub scale 42 patients (65.7%) scored more than 10 from maximum 15 points. Thirteen males (36.1%) and 8 females (25.8%) were engaged in full time paid employment. Three males and 2 females were full time students. Another 6 (19.4%) females did full time household work. Conclusions Patients on long term treatment with clozapine showed low levels of psychopathology. In the majority self care and other daily functions were adequate. Many patients treated with clozapine were engaged in full time employment. DOI: 10.4038/sljpsyc.v1i2.2574SL J Psychiatry 2010; 1 (2):47-50
机译：背景氯氮平是难治性精神分裂症的最有效治疗方法。有证据表明，氯氮平可改善社会和职业功能，并改善患者的生活质量。目的评估一组接受氯氮平治疗的患者的心理病理学和功能水平。方法招募了在两个月期间就诊于氯氮平诊所的67例患者。记录社会人口学特征，治疗时间和氯氮平剂量。使用心理病理学量表测量症状严重程度。使用“心理社会功能量表”评估功能水平。结果样本中男性占53.7％。多数年龄在20-39岁之间。在样品中，7.4％的患者接受氯氮平治疗两年或更短时间，3-5年使用38.8％进行治疗，6-10年使用40.3％。样品中43.3％的剂量为225-400 mg /天。在自我护理子量表中，61（95.3％）的满分为15，满分为13-15。在日常功能子量表中，有42位患者（65.7％）从最高的15分得到了10分以上。 13位男性（36.1％）和8位女性（25.8％）从事全职工作。全日制学生为三男两女。另外6位女性（19.4％）做全职家务。结论长期接受氯氮平治疗的患者精神病理学水平较低。在大多数情况下，自我保健和其他日常功能已足够。许多接受氯氮平治疗的患者全职工作。 DOI：10.4038 / sljpsyc.v1i2.2574SL J Psychiatry 2010; 1（2）：47-50

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号