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Early Poststroke Rehabilitation Using a Robotic Tilt-Table Stepper and Functional Electrical Stimulation

机译:使用机器人倾斜台步进器和功能性电刺激进行早期中风康复

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Background. Stroke frequently leaves survivors with hemiparesis. To prevent persistent deficits, rehabilitation may be more effective if started early. Early training is often limited because of orthostatic reactions. Tilt-table stepping robots and functional electrical stimulation (FES) may prevent these reactions.Objective. This controlled convenience sample study compares safety and feasibility of robotic tilt-table training plus FES (ROBO-FES) and robotic tilt-table training (ROBO) against tilt-table training alone (control). A preliminary assessment of efficacy is performed.Methods. Hemiparetic ischemic stroke survivors (age58.3±1.2years,4.6±1.2days after stroke) were assigned to 30 days of ROBO-FES (n=38), ROBO (n=35), or control (n=31) in addition to conventional physical therapy. Impedance cardiography and transcranial doppler sonography were performed before, during, and after training. Hemiparesis was assessed using the British Medical Research Council (MRC) strength scale.Results. No serious adverse events occurred; 8 patients in the tilt-table group prematurely quit the study because of orthostatic reactions. Blood pressure and CBFV dipped<10% during robot training. In 52% of controls mean arterial pressure decreased by≥20%. ROBO-FES increased leg strength by1.97±0.88points, ROBO by1.50±0.85more than control (1.03±0.61,P<0.05). CBFV increased in both robotic groups more than in controls (P<0.05).Conclusions. Robotic tilt-table exercise with or without FES is safe and may be more effective in improving leg strength and cerebral blood flow than tilt table alone.
机译:背景。中风常常使幸存者患有偏瘫。为了防止持续的赤字,如果尽早开始康复,可能会更有效。由于体位性反应,早期训练常常受到限制。倾斜台步进机器人和功能性电刺激(FES)可以防止这些反应。这项受控便利样本研究比较了机器人倾斜台训练加FES(ROBO-FES)和机器人倾斜台训练(ROBO)与仅倾斜台训练(对照)的安全性和可行性。方法进行了初步评估。偏瘫缺血性卒中幸存者(年龄58.3±1.2岁,卒中后4.6±1.2天)被指定为另外30天的ROBO-FES(n = 38),ROBO(n = 35)或对照组(n = 31)常规的物理治疗。在训练之前,期间和之后进行了阻抗心动图和经颅多普勒超声检查。使用英国医学研究理事会(MRC)强度量表对偏瘫进行评估。没有发生严重的不良事件;倾斜台组中有8名患者由于体位性反应而提前退出研究。在机器人训练期间,血压和CBFV下降了<10%。在52%的对照组中,平均动脉压下降了≥20%。 ROBO-FES使腿部力量比对照组增加1.97±0.88点,ROBO增加1.50±0.85点(1.03±0.61,P <0.05)。两组机器人的CBFV增幅均高于对照组(P <0.05)。带有或不带有FES的机器人倾斜台运动都是安全的,并且比单独倾斜台更有效地改善腿部力量和脑血流量。

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