• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sleep Science and Practice >Effect of postoperative positive airway pressure on risk of postoperative atrial fibrillation after cardiac surgery in patients with obstructive sleep apnea: a retrospective cohort study
【24h】

Effect of postoperative positive airway pressure on risk of postoperative atrial fibrillation after cardiac surgery in patients with obstructive sleep apnea: a retrospective cohort study

机译：阻塞性睡眠呼吸暂停患者术后气道正压对心脏手术后房颤风险的影响：一项回顾性队列研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BackgroundObstructive sleep apnea (OSA) is a known risk factor for postoperative atrial fibrillation (POAF) after cardiac surgery. However, whether better management of OSA reduces the risk of POAF remains unknown. The aim of this study was to determine if postoperative positive airway pressure (PAP) treatment for OSA reduces POAF risk after cardiac surgery. PAP included both continuous and bilevel positive airway pressure. MethodsThis retrospective cohort study was conducted at Stanford University teaching hospital. We included a total of 152 OSA patients with preoperative electrocardiography showing sinus rhythm who underwent coronary artery bypass grafting (CABG), aortic valve replacement, mitral valve repair/replacement, or combined valve and CABG surgery from October 2007 to September 2014. Postoperative PAP use status was determined by reviewing electronic health records. The primary outcome was time to incident POAF. We reviewed records from the time of surgery to hospital discharge. Multivariate Cox regression model was used to calculate the adjusted hazard ratio of postoperative PAP in association with risk of POAF. ResultsOf the 152 OSA patients included for analysis, 86 (57%) developed POAF, and 76 (50%) received postoperative PAP treatment. POAF occurred in 37 (49%) of the patients receiving postoperative PAP, compared with 49 (65%) of those not receiving postoperative PAP (unadjusted p value?=?0.33). Multivariable Cox regression analysis of time to incident POAF did not show an association between postoperative PAP treatment and risk of POAF (adjusted hazard ratio: 0.93 [95%CI: 0.58 – 1.48]). There were no significant differences in other postoperative complications between the two groups. ConclusionsThe study did not find an association between postoperative PAP treatment and risk of POAF after cardiac surgery in patients with OSA. Future prospective randomized trials are needed to investigate this issue further.
机译：背景阻塞性睡眠呼吸暂停（OSA）是心脏手术后发生心房纤颤（POAF）的已知危险因素。但是，是否更好地管理OSA是否可以降低POAF的风险尚不清楚。这项研究的目的是确定OSA的术后气道正压（PAP）治疗是否可以降低心脏手术后的POAF风险。 PAP包括连续和双水平气道正压。方法这项回顾性队列研究是在斯坦福大学教学医院进行的。我们纳入了2007年10月至2014年9月共152例OSA术前心电图的患者，这些患者显示窦性心律，接受了冠状动脉旁路移植术（CABG），主动脉瓣置换，二尖瓣修复/置换或瓣膜和CABG联合手术。状况是通过查看电子健康记录来确定的。主要结果是发生POAF的时间。我们回顾了从手术到出院的记录。采用多元Cox回归模型来计算术后PAP与POAF风险的调整风险比。结果在纳入分析的152名OSA患者中，有86名（57％）发生了POAF，76名（50％）接受了术后PAP治疗。在接受术后PAP的患者中，有37例（49％）发生了POAF，而未接受术后PAP的患者中有49例（65％）（未调整的p值== 0.33）。发生POAF的时间的多变量Cox回归分析未显示术后PAP治疗与POAF风险之间存在关联（调整后的危险比：0.93 [95％CI：0.58 – 1.48]）。两组在其他术后并发症方面无显着差异。结论该研究未发现OSA患者术后PAP治疗与心脏手术后POAF风险之间存在关联。需要进一步的前瞻性随机试验来进一步研究该问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号