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Can 6-minute walk test predict severity of obstructive sleep apnea syndrome?

机译：6分钟步行测试能否预测阻塞性睡眠呼吸暂停综合症的严重程度？

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Background When considering the benefits of the 6-min walking test (6-MWT) in research fields and the need of treatment for moderate to severe obstructive sleep apnea (OSA) patients, research in this field is of great advantage and may have a significant role in therapeutic grounds. Methods This cross-sectional study was conducted on 47 patients with confirmed diagnosis of OSA in the National Research Institute of Tuberculosis and Lung Disease, Masih Daneshvari Hospital. The 6-MWT was performed the day after polysomnography. The correlation between the 6-MWT and paraclinical findings during polysomnography in OSA patients was investigated . Results In cases with moderate to severe OSA, the male sex displayed correlation with high PCO2. Ages of patients examined displayed reversed correlation with the distance in the 6-MWT by observing the O2 saturation (Sat) at the end of the 6-MWT, displaying direct correlation with the duration of O2 Sat 90% during sleep. The BMI also showed reversed correlation with the distance in the 6-MWT. Similarly, the severity of the OSA had reversed correlation with the expected distance in the test. However, patients with higher duration of O2 Sat 90% during sleep had a higher reduction in O2 Sat during and after the 6-MWT. Patients with higher duration of O2 Sat 90% during sleep also completed less overall distance in the 6-MWT ( P values 0.05 for all). Conclusion It appears that the 6-MWT can be used in patients with OSA to predict severity of the desaturation in OSA beyond functional capacity. Also, it can help predict the severity of disease and assist in follow up of the OSA patients in terms of functional capacity and selection of the most appropriate treatment strategy to increase the physical ability of the patients.
机译：背景技术考虑到6分钟步行测试（6-MWT）在研究领域的益处以及对中度至重度阻塞性睡眠呼吸暂停（OSA）患者进行治疗的需求，该领域的研究具有很大的优势，并且可能具有重要意义。在治疗方面的作用。方法本横断面研究是在Masih Daneshvari医院的国家结核病和肺病研究所对47例确诊为OSA的患者进行的。多导睡眠图检查后的第二天进行6-MWT。研究了OSA患者多导睡眠图期间6-MWT与临床旁发现之间的相关性。结果在中度至重度OSA患者中，男性表现出与高PCO2的相关性。通过观察6-MWT结束时的O2饱和度（Sat），检查的患者年龄与6-MWT中的距离呈反向相关，与睡眠期间O2 Sat的持续时间<90％直接相关。 BMI也显示与6MWT中距离的反向相关。同样，OSA的严重性与测试中的预期距离具有相反的相关性。但是，在睡眠期间O2 Sat持续时间较长的患者（<90％）在6-MWT期间和之后O2 Sat的降低较高。睡眠期间O2 Sat持续时间较长的患者<90％，6-MWT中的总距离也较小（所有P值均<0.05）。结论6-MWT似乎可用于OSA患者，以预测OSA脱饱和的严重程度超出功能范围。而且，它可以帮助预测疾病的严重程度，并在功能能力和选择最合适的治疗策略以提高患者身体能力方面协助OSA患者的随访。

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