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首页> 外文期刊>Sleep Disorders >Clinical Features and Polysomnographic Findings in Greek Male Patients with Obstructive Sleep Apnea Syndrome: Differences Regarding the Age
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Clinical Features and Polysomnographic Findings in Greek Male Patients with Obstructive Sleep Apnea Syndrome: Differences Regarding the Age

机译：希腊男性阻塞性睡眠呼吸暂停综合症的临床特征和多导睡眠图检查结果：年龄差异

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Background-Aim. Although sleep disturbance is a common complaint among patients of all ages, research suggests that older adults are particularly vulnerable. The aim of this retrospective study was to elucidate the influence of age on clinical characteristics and polysomnographic findings of obstructive sleep apnea syndrome (OSAS) between elderly and younger male patients in a Greek population.Methods. 697 male patients with OSAS were examined from December 2001 to August 2011. All subjects underwent an attended overnight polysomnography (PSG). They were divided into two groups: young and middle-aged (<65 years old) and elderly (≥65 years old). We evaluated the severity of OSAS, based on apnea-hypopnea index (AHI), and the duration of apnea-hypopnea events, the duration of hypoxemia during total sleep time (TST) and during REM and NREM sleep, and the oxygen saturation in REM and in NREM sleep.Results. PSG studies showed that elderly group had significant higher duration of apnea-hypopnea events, longer hypoxemia in TST and in NREM sleep, as well as lower oxygen saturation in REM and NREM sleep than the younger group. Otherwise, significant correlation between BMI and neck circumference with AHI was observed in both groups.Conclusions. The higher percentages of hypoxemia during sleep and longer duration of apnea-hypopnea events that were observed in the elderly group might be explained by increased propensity for pharyngeal collapse and increased deposition of parapharyngeal fat, which are associated with aging. Another factor that could explain these findings might be a decreased partial arterial pressure of oxygen (PaO2) due to age-related changes in the respiratory system.
机译：背景目标。尽管睡眠障碍是所有年龄段患者的普遍抱怨，但研究表明，老年人特别容易受到伤害。这项回顾性研究的目的是阐明年龄对希腊人群中老年男性和年轻男性阻塞性睡眠呼吸暂停综合症（OSAS）的临床特征和多导睡眠图检查结果的影响。从2001年12月至2011年8月，对697例OSAS男性患者进行了检查。所有受试者均接受了夜间多导睡眠图检查（PSG）。他们分为两组：年轻人和中年（<65岁）和老人（≥65岁）。我们根据呼吸暂停低通气指数（AHI），呼吸暂停低通气事件的持续时间，总睡眠时间（TST）以及REM和NREM睡眠期间的低氧血症持续时间以及REM中的氧饱和度评估了OSAS的严重程度然后进入NREM睡眠状态。 PSG研究表明，与年轻组相比，老年组的呼吸暂停-呼吸不足事件持续时间明显延长，TST和NREM睡眠中的低氧血症时间更长，REM和NREM睡眠中的氧饱和度更低。否则，两组均观察到BMI和颈围与AHI之间存在显着相关性。老年人中睡眠中低氧血症的百分比较高，呼吸暂停-呼吸不足事件的持续时间较长，这可能是由于咽部塌陷倾向增加和咽旁脂肪沉积增加（与衰老有关）所致。可以解释这些发现的另一个因素可能是由于呼吸系统中与年龄相关的变化而导致的氧气分压（PaO2）降低。

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