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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Differences in Pain Intensity of Tumors Spread to the Anterior versus Anterolateral/Lateral Portions of the Vertebral Body Based on CT Scans
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Differences in Pain Intensity of Tumors Spread to the Anterior versus Anterolateral/Lateral Portions of the Vertebral Body Based on CT Scans

机译：基于CT扫描的肿瘤疼痛强度分布到椎体的前部和前外侧/侧面部分的差异

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We investigated whether the intensity of cancer pain differs for malignant tumors that have spread to anterior or anterolateral/lateral portions of the vertebral body. We hypothesize that tumor spread to the anterolateral/lateral vertebral body elicits more serious pain due to increased irritation of the spinal nerve. The selection criteria were as follows: (1) advanced or metastatic solid tumor; (2) radicular pain without extremity weakness; (3) malignant lesions anteriorly, anterolaterally, or laterally located at the vertebral body either spread locoregionally or over a greater distance via metastasis based on CT scan diagnosis; and (4) patient needs to use opioids for pain relief. Severe spinal pain intensity was defined as spinal pain for which patients required either strong opioids or spinal irradiation for relief. Eighty-six patients were enrolled in the study. Bone lesions were mainly osteolytic. Thirty-nine tumors spread to the vertebral body in the anterior direction, and 47 in the anterolateral/lateral direction. Severe pain intensity related to vertebral body lesions was due to anterolateral/lateral spread, primary sites of nonurothelial carcinoma, metastatic vertebral lesions, multiple lesions within a vertebrum, and location within the cervical-thoracic spine. In conclusion, patients with tumor spread to the anterolateral/lateral portion of vertebrae bodies based on CT scan diagnosis experienced severe cancer pain. These patients needed strong opioids or palliative spinal irradiation for pain relief.
机译：我们调查了癌症疼痛的强度对于已经扩散到椎体的前部或前外侧/外侧部分的恶性肿瘤是否有所不同。我们假设肿瘤扩散到前外侧/外侧椎体会引起更严重的疼痛，这是由于脊神经的刺激性增加所致。选择标准如下：（1）晚期或转移性实体瘤; （2）神经根疼痛，无四肢无力; （3）基于CT扫描诊断，通过转移在椎体的前，前，前，后侧的恶性病变局部或局部扩散。 （4）患者需要使用阿片类药物缓解疼痛。严重的脊柱疼痛强度定义为患者需要强阿片类药物或脊柱照射以缓解疼痛的脊柱疼痛。八十六名患者被纳入研究。骨病变主要是溶骨性的。 39例肿瘤在前方向扩散到椎体，而47例在前外侧/侧面方向扩散。与椎体病变相关的剧烈疼痛强度是由于前外侧/外侧扩散，非尿路上皮癌的主要部位，转移性椎体病变，椎体内多处病变以及颈胸椎内的位置所致。总之，根据CT扫描诊断，肿瘤扩散到椎体的前外侧/外侧部分的患者经历了严重的癌痛。这些患者需要强效阿片类药物或姑息性脊柱照射以缓解疼痛。

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