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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Quality of Life in Painful Peripheral Neuropathies: A Systematic Review
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Quality of Life in Painful Peripheral Neuropathies: A Systematic Review

机译：疼痛性周围神经病变的生活质量：系统评价

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Objective. Neuropathic pain is a common presenting complaint of patients with peripheral neuropathy (PN) and is considered one of the most disabling neuropathic symptoms, with detrimental effects on patients’ quality of life (QoL). The aim of this review was to overview the current literature that focuses on QoL in painful PN of various aetiologies. We sought to clarify the direct effect of pain and its treatment on patients’ QoL. Methodology. A systematic computer-based literature search was conducted using the PubMed database to search for papers on QoL in painful PN. Information was extracted regarding prevalence, demographics, and response to treatment where relevant. Results. We identified 66 articles eligible for inclusion. The vast majority of studies () focused on patients with diabetic PN. Other aetiologies of painful PN where QoL has been studied to date include gluten, immune-mediated, HIV, chemotherapy-induced, and chronic idiopathic axonal polyneuropathy. Pharmacological treatment is the mainstay in managing pain and has a direct positive and independent effect on the overall QoL. Other nonpharmacological approaches can also be of benefit, either alone or as adjuvant treatments, and are discussed. Conclusion. The findings demonstrate that QoL is impaired in painful PN and should not be neglected in clinical practice. Patients’ pain management and subsequent impact on QoL should routinely be assessed and monitored.
机译：目的。神经性疼痛是周围神经病（PN）患者的常见症状，被认为是最致残的神经性症状之一，对患者的生活质量（QoL）有不利影响。这篇综述的目的是概述针对各种病因的疼痛性PN中的QoL的当前文献。我们试图弄清疼痛及其对患者生活质量的直接影响。方法。使用PubMed数据库进行了系统的基于计算机的文献搜索，以搜索有关疼痛性PN中QoL的论文。提取有关患病率，人口统计学和相关治疗反应的信息。结果。我们确定了66篇符合纳入条件的文章。绝大多数研究（）都针对糖尿病性PN患者。迄今为止，已对QoL进行过研究的疼痛性PN的其他病因包括面筋，免疫介导，HIV，化学疗法诱发的和慢性特发性轴索性多发性神经病。药理学治疗是控制疼痛的主要手段，对总体生活质量具有直接的积极和独立的影响。其他非药物学方法也可能有益，无论是单独使用还是作为辅助治疗，都将进行讨论。结论。研究结果表明，QoL在疼痛性PN中受损，在临床实践中不应忽略。应常规评估和监测患者的疼痛管理以及对生活质量的后续影响。

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