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首页> 外文期刊>Pakistan journal of medical sciences. >Frequency of cirrhotic cardiomyopathy in patients with cirrhosis of liver: A tertiary care hospital experience
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Frequency of cirrhotic cardiomyopathy in patients with cirrhosis of liver: A tertiary care hospital experience

机译：肝硬化患者肝硬化性心肌病的发生频率：三级医院的经验

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Objective: To determine the frequency of cirrhotic cardiomyopathy in patients with liver cirrhosis. Methodology: This Descriptive case series study was conducted in ?Medical Department of Liaquat University Hospital Jamshoro / Hyderabad from 3rd January 2009 to 16th June 2009.This study included 74 consecutive ?cases of cirrhosis of liver of either sex above 14 years of age. Firstly, resting ECG was done in all the patients. QTc values were calculated from lead II. QTc interval of > 0.44 sec were considered as prolonged. Systolic dysfunction was assessed by ejection fraction (value of >55% was considered as increased). Diastolic dysfunction manifested by reduced E/A ratio (0.44sec) in 16 (21.6%), Ejection fraction (EF) > 0. 55 was present in 25 (33.8%) patients. Cirrhotic cardiomyopathy was present in 33(44.6%) cases. A strong relation was found between cardiomyopathy and severity of cirrhosis of liver (p=0.001), pr0-Bnp levels (p=0.003), QTc > 44 sec (0.004), Ejection fraction > 55% (0.004) and E/A ratio < 1 (p=0.005). Conclusion: Cirrhotic cardiomyopathy was present in a sizeable proportion of cirrhotic patients, more so in the later stages of cirrhosis of liver.
机译：目的：确定肝硬化患者肝硬化性心肌病的发生频率。方法：该描述性病例系列研究于2009年1月3日至2009年6月16日在利亚夸特大学医院Jamshoro / Hyderabad的医学科进行，该研究包括74例14岁以上的肝硬化患者。首先，对所有患者进行静息心电图检查。 QTc值由导联II计算得出。 QTc间隔> 0.44秒被认为是延长的。通过射血分数评估收缩功能障碍（> 55％的值被认为增加）。舒张功能障碍表现为16例（21.6％）的E / A比降低（0.44sec），射血分数（EF）>0。25例（33.8％）患者存在55。肝硬化性心肌病33例（44.6％）。心肌病与肝硬化严重程度（p = 0.001），pr0-Bnp水平（p = 0.003），QTc> 44秒（0.004），射血分数> 55％（0.004）和E / A比之间存在密切关系<1（p = 0.005）。结论：肝硬化性心肌病在相当大比例的肝硬化患者中存在，在肝硬化的晚期阶段更是如此。

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