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Common infusion-related reactions to subcutaneous immunoglobulin therapy: Managing patient expectations

机译:皮下免疫球蛋白治疗的常见输注相关反应:管理患者期望

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Objective: The availability of weekly subcutaneous infusions of subcutaneous immunoglobulin (SCIg) provides an additional therapeutic option for patients with primary immunodeficiency disease. With proper patient education, individuals can safely transition to SCIg therapy and experience minimal side effects.Research design: Case reports.Results: A plan for successful implementation of SCIg therapy is presented. Case reports illustrate the how to manage the transition from IVIg to home infusion of SCIg. In Case 1, despite training, home infusion was complicated by infusion-site reactions, the most common adverse event. Troubleshooting by the medical staff identified improper administration of SCIg, a correctable cause of reactions. In Case 2, patient education enabled this woman to successfully transition to SCIg without adverse effects, and without the headache and fatigue she experienced with IVIg.Conclusions: Home infusion of SCIg can be successfully implemented with careful planning, patient/caregiver education, support, and follow-up.
机译:目的:每周一次皮下输注皮下免疫球蛋白(SCIg)的可用性为原发性免疫缺陷病患者提供了另一种治疗选择。通过适当的患者教育,个人可以安全地过渡到SCIg治疗,并且副作用最小。研究设计:病例报告结果:提出了成功实施SCIg治疗的计划。案例报告说明了如何管理从IVIg到SCIg家庭输液的过渡。在案例1中,尽管进行了培训,但家庭输液却由于输液部位反应(最常见的不良事件)而变得复杂。医务人员进行的故障排除确定了SCIg的管理不当,这是可纠正的反应原因。在案例2中,患者教育使该名妇女成功过渡到SCIg,而没有不良反应,并且没有IVIg所经历的头痛和疲劳。结论:通过精心计划,患者/护理人员教育,支持,和跟进。

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