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An evaluation of patients’ adherence with hypoglycemic medications among Papua New Guineans with type 2 diabetes: influencing factors

机译:巴布亚新几内亚2型糖尿病患者对降糖药物依从性的评估:影响因素

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Purpose: The aims of this study were to evaluate the extent of adherence to hypoglycemic medications, assess the relationship between adherence and glycemic control, and evaluate factors affecting adherence.Research design and methods: This was a cross-sectional study of patients with established type 2 diabetes attending the Port Moresby General Hospital Diabetes Clinic. Face-to-face interviews were conducted using a questionnaire designed for the study and data were collected concerning the 3 months prior to interview. The questionnaire covered demographic details, lifestyle, biochemical and physical measurements, and medication management. Glycemic control was investigated among patients adhering to their medications (not missing doses) to different degrees (100%, 95%, 90%, and 80%). Results: Of a total of 356 participants who were prescribed hypoglycemic medications, 59.6% omitted some of their doses. Age appeared to have a significant impact on adherence at some levels of adherence, with those aged >60 years being more likely to be adherent (logistic regression). Those who were 95%–99% and those who were 10% (85.5 mmol/mol). Multiple factors were identified as contributors to nonadherence, with patient-based issues (86.0%) and the health care system (21.7%) being the most common.Conclusion: This study showed a significant level of nonadherence among patients with type 2 diabetes in Papua New Guinea. Nonadherence to medication appeared to be associated with poor glycemic control and was due to a variety of reasons. Future interventions aimed at improving adherence will need to take these into account.
机译:目的:本研究的目的是评估对低血糖药物依从性的程度,评估依从性与血糖控制之间的关系,以及评估影响依从性的因素。研究设计和方法:这是对既往型患者的横断面研究2名糖尿病患者正在莫尔兹比港综合医院糖尿病诊所就诊。使用专为该研究设计的问卷进行面对面访谈,并收集访谈前3个月的数据。问卷涵盖了人口统计的详细信息,生活方式,生化和物理测量以及药物管理。在不同程度(100%,95%,90%和80%)坚持用药(不丢失剂量)的患者中研究了血糖控制。结果:在总共356位接受降血糖药物治疗的参与者中,有59.6%的人省略了部分剂量。在一定程度的依从性上,年龄似乎对依从性有重大影响,> 60岁的人更容易依从(逻辑回归)。那些为95%–99%,那些为10%(85.5 mmol / mol)。多种因素被认为是导致患者不依从的原因,其中以患者为基础的问题(占86.0%)和卫生保健系统(21.7%)是最常见的。结论:这项研究表明,巴布亚2型糖尿病患者中存在严重的不依从性新几内亚。对药物的不依从性似乎与不良的血糖控制有关,这是由于多种原因造成的。未来旨在提高依从性的干预措施将需要考虑到这些。

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