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Patient willingness for repeat screening?and preference for CT colonography and?optical colonoscopy in ACRIN 6664: the National CT Colonography trial

机译:病人愿意重复筛查,并愿意接受ACRIN 6664中的CT结肠镜检查和光学结肠镜检查:美国国家CT结肠镜检查

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Background: Current American Cancer Society recommendations for colon cancer screening include optical colonoscopy every 10 years or computed tomography colonography (CTC) every 5 years. Bowel preparation (BP) is currently required for both screening modalities.Purpose: To compare ACRIN 6664: the National CT Colonography Trial (NCTCT) participant experiences with CTC and optical colonoscopy (OC), procedure preference, and willingness to return for each procedure.Materials and methods: Participants from fifteen NCTCT sites, who underwent CTC followed by OC under sedation, were invited to complete questionnaires 2 weeks postexam, asking about procedure preference, physical discomfort, and embarrassment experienced and whether that discomfort and embarrassment was better or worse than expected during BP, CTC, and OC, as well as willingness to return for repeat CTC and OC at different time intervals.Results: A total of 2,310 of 2,600 patients (89%) returned their questionnaires. Of patients reporting a preference, 1,058 (46.6%) preferred CTC, 569 (25.0%) preferred OC, and 626 (27.6%) reported no preference. Participant-reported discomfort worse than expected differed significantly between CTC (32.9%) and OC (5.0%) (P<0.001). About 79.3% were willing to be screened again with CTC in 5 years, and 96.6% with OC in 10 years. Discomfort and embarrassment worse than expected with OC were associated with increased intention to adhere with CTC in the future. Conversely, embarrassment experienced during CTC and discomfort worse than expected on CTC were associated with increased intention to adhere with OC in the future.Conclusion: While a larger proportion of participants indicated that they preferred CTC to OC, willingness to undergo repeat CTC compared to OC was limited by unanticipated exam discomfort and embarrassment and CTC’s shorter screening interval.
机译:背景:美国癌症协会目前对结肠癌筛查的建议包括每10年进行光学结肠镜检查或每5年进行计算机断层扫描结肠造影(CTC)。两种筛查方法目前都需要进行肠道准备(BP)。目的:比较ACRIN 6664:美国国家CT结肠造影试验(NCTCT)参与者的CTC和光学结肠镜检查(OC)经验,程序偏爱以及愿意返回每种程序。材料和方法:邀请来自15个NCTCT站点的参与者进行CTC,然后在镇静下进行OC,在检查后2周完成问卷调查,询问程序偏好,身体不适和所遇到的尴尬,以及该不适和尴尬是好于还是差于结果:在2,600例患者中,共有2,310例患者(89%)返回了问卷,他们希望在BP,CTC和OC期间获得期望,并愿意在不同的时间间隔再次进行CTC和OC。在报告有偏爱的患者中,有1,058(46.6%)个偏爱的CTC,569(25.0%)个偏爱的OC和626(27.6%)个没有偏爱的患者。参与者报告的不适感比预期的差,CTC(32.9%)和OC(5.0%)之间有显着差异(P <0.001)。愿意在5年内再次进行CTC筛查的患者约为79.3%,并且愿意在10年内进行OC筛查的比例为96.6%。 OC带来的不适和尴尬情况比预期的要严重,这与将来加入CTC的意愿增加有关。相反,在CTC期间遇到的尴尬和不适感比CTC差,这与将来坚持OC的意愿增加有关。结论:虽然较大比例的参与者表示他们比OC更喜欢CTC,但愿意接受重复CTC而不是OC由于出乎意料的考试不适和尴尬以及CTC较短的检查间隔而受到限制。

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