• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Patient Preference and Adherence >Impact of patient programs on adherence and persistence in inflammatory and immunologic diseases: a?meta-analysis
【24h】

Impact of patient programs on adherence and persistence in inflammatory and immunologic diseases: a?meta-analysis

机译：患者项目对炎性和免疫性疾病依从性和持久性的影响：元分析

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives: Patient adherence and persistence is important to improve outcomes in chronic conditions, including inflammatory and immunologic (I&I) diseases. Patient programs that aim at improving medication adherence or persistence play an essential role in optimizing care. This meta-analysis assessed the effectiveness of patient programs in the therapeutic area of I&I diseases.Methods: A global systematic literature review was conducted with inclusion criteria of: patient programs in I&I diseases; published in English language between January 2008 and September 2013; and reporting measures of adherence or persistence, including medication possession ratio >80% and persistence rate. A meta-analysis was performed using a random effects model. Subgroup analyses based on the type of program was performed whenever feasible.Results: Of 67 studies reviewed for eligibility, a total of 17 studies qualified for inclusion in the meta-analysis. Overall, patient programs increased adherence (odds ratio [OR]=2.48, 95% confidence interval [CI]=1.68–3.64, P<0.00001) as compared with standard of care. Combination patient programs that used both informational and behavioral strategies were superior in improving adherence (OR=3.68, 95% CI=2.20–6.16, P<0.00001) compared with programs that used only informational (OR=2.16, 95% CI=1.36–3.44, P=0.001) or only behavioral approaches (OR=1.85, 95% CI=1.00–3.45, P=0.05). Additionally, patients were more likely to be persistent (OR=2.26, 95% CI=1.16–4.39, P=0.02) in the intervention group as compared with the control group. Persistence (in days) was significantly (P=0.007) longer, by 42 additional days, in the intervention group than in the control group.Conclusions: Patient programs can significantly improve adherence as well as persistence in the therapeutic area of I&I diseases. Programs employing a multimodal approach are more effective in improving adherence than programs with informational or behavioral strategies alone. This in turn may improve patient outcomes.
机译：目标：患者的坚持和坚持对改善包括炎症和免疫（I＆I）疾病在内的慢性疾病的结果至关重要。旨在改善药物依从性或持久性的患者计划在优化护理中起着至关重要的作用。该荟萃分析评估了患者计划在I＆I疾病治疗领域中的有效性。方法：对全球系统文献进行回顾，纳入标准包括：I＆I疾病患者计划;在2008年1月至2013年9月之间以英语发布;并报告坚持或坚持的措施，包括药物拥有率> 80％和坚持率。使用随机效应模型进行荟萃分析。在可行的情况下，根据程序类型进行亚组分析。结果：在67项纳入研究的研究中，共有17项研究符合纳入荟萃分析的条件。总体而言，与标准治疗相比，患者计划增加了依从性（赔率[OR] = 2.48，95％置信区间[CI] = 1.68–3.64，P <0.00001）。与仅使用信息性方案（OR = 2.16，95％CI = 1.36-P）相比，既使用信息性方案又采用行为策略的联合患者方案在改善依从性方面（OR = 3.68，95％CI = 2.20–6.16，P <0.00001）要好得多。 3.44，P = 0.001）或仅行为方式（OR = 1.85，95％CI = 1.00–3.45，P = 0.05）。此外，与对照组相比，干预组患者更有可能持续存在（OR = 2.26，95％CI = 1.16-4.39，P = 0.02）。与对照组相比，干预组的持续时间（以天为单位）显着（P = 0.007）长了42天。结论：患者程序可以显着改善I＆I疾病治疗领域的依从性和持续性。与仅采用信息或行为策略的计划相比，采用多模式方法的计划在提高依从性方面更为有效。反过来，这可以改善患者的预后。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号